Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D01326)
Name
Pegvaliase
Synonyms    Click to Show/Hide the Synonyms of This API
Pegvaliase; rAvPAL-PEG; PEG-PAL; Pegvaliase [INN]; UNII-N6UAH27EUV; Phenylase; Pegvaliase-pqpz; BMN 165; N6UAH27EUV; 1585984-95-7; DB12839; (2S)-2-amino-6-[6-(2-methoxyethoxy)hexanoylamino]hexanoic acid
Clinical Status
Approved
PubChem CID
86278362
Formula
C15H30N2O5
Canonical SMILES
COCCOCCCCCC(=O)NCCCC[C@@H](C(=O)O)N
InChI
1S/C15H30N2O5/c1-21-11-12-22-10-6-2-3-8-14(18)17-9-5-4-7-13(16)15(19)20/h13H,2-12,16H2,1H3,(H,17,18)(H,19,20)/t13-/m0/s1
InChIKey
NPOCDVAOUKODSQ-ZDUSSCGKSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=86278362"></iframe>
3D MOL is unavailable 2D MOL
Physicochemical Properties Molecular Weight 318.41 Topological Polar Surface Area 111
XlogP -2.3 Complexity 300
Heavy Atom Count 22 Rotatable Bond Count 15
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 6
Full List of Drug Formulations (DFMs) Containing This API
          Pegvaliase 10mg/0.5 ml Injection Click to Show/Hide the Full List of Formulation(s):          1 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium Chloride; Trans-Cinnamic Acid; Tromethamine; Tromethamine Hydrochloride
                   Dosage Form Injection
                   Company Biomarin Pharmaceutical
          Pegvaliase 2.5mg/0.5 ml Injection Click to Show/Hide the Full List of Formulation(s):          1 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium Chloride; Trans-Cinnamic Acid; Tromethamine; Tromethamine Hydrochloride
                   Dosage Form Injection
                   Company Biomarin Pharmaceutical
          Pegvaliase 20 mg/ml Injection Click to Show/Hide the Full List of Formulation(s):          1 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium Chloride; Trans-Cinnamic Acid; Tromethamine; Tromethamine Hydrochloride
                   Dosage Form Injection
                   Company Biomarin Pharmaceutical

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