Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET08IYY) | |||||
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| Name |
ABHD5-Perilipin complex (ABHD5-PLIN1)
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| Synonyms |
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Abhydrolase domain-containing protein 5 complexed with Lipid droplet-associated protein; Abhydrolase domain-containing protein 5 complexed with Perilipin-1; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 complexed with Lipid droplet-associated protein; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 complexed with Perilipin-1; Lipid droplet-binding protein CGI-58 complexed with Perilipin-1; Lipid droplet-binding protein CGI-58 complexed with Lipid droplet-associated protein
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| Family | Transferase (TFase) >> Acyltransferase (EC 2.3) | ||||
| Organism |
Homo sapiens (Human)
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| UniProt ID | ABHD5_HUMAN | (click to find more protein-related data of this DBT) | |||
| PLIN1_HUMAN | (click to find more protein-related data of this DBT) | ||||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Cysteine hydrochloride | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Antioxidant
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 7335 nM (estimated based on the structural similarity with CHEMBL1426508 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.826086957 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | ABHD5_HUMAN ; PLIN1_HUMAN | |||||
| References | |||||
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| 1 | PubChem BioAssay data set. | ||||
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