Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0AY8Y) | |||||
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| Name |
Protein kinase C (RKC)
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| Family | Transferase (TFase) >> Kinase (EC 2.7) | ||||
| Organism |
Homo sapiens (Human)
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| UniProt ID | KPCA_HUMAN | (click to find more protein-related data of this DBT) | |||
| KPCB_HUMAN | (click to find more protein-related data of this DBT) | ||||
| KPCD_HUMAN | (click to find more protein-related data of this DBT) | ||||
| KPCE_HUMAN | (click to find more protein-related data of this DBT) | ||||
| KPCG_HUMAN | (click to find more protein-related data of this DBT) | ||||
| KPCL_HUMAN | (click to find more protein-related data of this DBT) | ||||
| KPCT_HUMAN | (click to find more protein-related data of this DBT) | ||||
| KPCZ_HUMAN | (click to find more protein-related data of this DBT) | ||||
| TTD ID | T88318 | (click to find more therapeutic target data of this DBT) | |||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Tricaprin | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
click to show the detail info of this DIG
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Emollient
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 10000 nM (estimated based on the structural similarity with CHEMBL26341 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.978723404 | |||||
| Tested Species | Rattus norvegicus (Rat) | |||||
| UniProt ID | KPCA_RAT ; KPCB_RAT ; KPCD_RAT ; KPCE_RAT ; KPCG_RAT ; KPCL_RAT ; KPCT_RAT ; KPCZ_RAT | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | The synthesis and evaluation of diacylglycerol analogues as potential second-messenger antagonists. Bioorg Med Chem Lett. (1992) 2:127-130. | ||||
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