Details of the Biological Target of DIG (DBT)
General Information of DBT (ID: ET0AY8Y) | |||||
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Name |
Protein kinase C (RKC)
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Family | Transferase (TFase) >> Kinase (EC 2.7) | ||||
Organism |
Homo sapiens (Human)
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UniProt ID | KPCA_HUMAN | (click to find more protein-related data of this DBT) | |||
KPCB_HUMAN | (click to find more protein-related data of this DBT) | ||||
KPCD_HUMAN | (click to find more protein-related data of this DBT) | ||||
KPCE_HUMAN | (click to find more protein-related data of this DBT) | ||||
KPCG_HUMAN | (click to find more protein-related data of this DBT) | ||||
KPCL_HUMAN | (click to find more protein-related data of this DBT) | ||||
KPCT_HUMAN | (click to find more protein-related data of this DBT) | ||||
KPCZ_HUMAN | (click to find more protein-related data of this DBT) | ||||
TTD ID | T88318 | (click to find more therapeutic target data of this DBT) | |||
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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DIG Name: Tricaprin | Click to Show/Hide | |||||
Detailed Information |
DIG Info
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Functional Class | Click to Show/Hide the Functional Class of This DIG
Emollient
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Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
Biological Activity | IC50 = 10000 nM (estimated based on the structural similarity with CHEMBL26341 ) | [1] | ||||
Structural Similarity | Tanimoto coefficient = 0.978723404 | |||||
Tested Species | Rattus norvegicus (Rat) | |||||
UniProt ID | KPCA_RAT ; KPCB_RAT ; KPCD_RAT ; KPCE_RAT ; KPCG_RAT ; KPCL_RAT ; KPCT_RAT ; KPCZ_RAT | |||||
References | |||||
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1 | The synthesis and evaluation of diacylglycerol analogues as potential second-messenger antagonists. Bioorg Med Chem Lett. (1992) 2:127-130. | ||||
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