Details of the Biological Target of DIG (DBT)

General Information of DBT (ID: ET0E6QN)
Name	Leukemia RAW264.7 cells (RAW264.7)
Synonyms	Click to Show/Hide the Synonyms of This DBT Mouse leukemia RAW264.7 cells; RAW264; RAW2647; RAW264.7; RAW-264.7; Raw 264.7; Raw264.7
Family	Cell line (CELL) >> Ascites cell line (ASCcel)
Organism	Mus musculus (Mouse)
Cellosaurus ID	CVCL_0493	(click to find more cell line data of this DBT)

Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
DIG Name: Cis-vanillin 2,3-butanediol acetal		Click to Show/Hide
Detailed Information	DIG Info click to show the detail info of this DIG
Functional Class	Click to Show/Hide the Functional Class of This DIG Flavoring agent
Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
Biological Activity	IC50 = 29200 nM (estimated based on the structural similarity with CHEMBL4474585 )		[1]
Structural Similarity	Tanimoto coefficient = 0.928571429
Tested Species	Mus musculus (Mouse)
Cellosaurus ID	CVCL_0493
DIG Name: Sodium lauryl sulfate		Click to Show/Hide
Detailed Information	DIG Info click to show the detail info of this DIG
Functional Class	Click to Show/Hide the Functional Class of This DIG Emulsifying agent; Modified-release agent; Penetration agent; Solubilizing agent; Surfactant; lubricant
Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
Biological Activity	IC50 > 100000 nM (tested by experiment)		[2]
Tested Species	Mus musculus (Mouse)
Cellosaurus ID	CVCL_0493

References
1	Anti-inflammatory Ellagitannins from Cleidion brevipetiolatum for the Treatment of Rheumatoid Arthritis. J Nat Prod. 2019 Sep 27; 82(9):2409-2418.
2	Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes. Med Chem Comm. (2014) 5:25-31.

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