Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0I0MK) | |||||
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| Name |
Ovarian cancer ADR-RES cells (NCI/ADR-RES)
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| Synonyms |
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Human ovarian adenocarcinoma NCI/ADR-RES cells; NCI-ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR
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| Family | Cell line (CELL) >> Ovary cell line (OVAcel) | ||||
| Organism |
Homo sapiens (Human)
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| Cellosaurus ID | CVCL_1452 | (click to find more cell line data of this DBT) | |||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Acetdimethylamide | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Solvent
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 40000 nM (estimated based on the structural similarity with CHEMBL316041 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.793103448 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| Cellosaurus ID | CVCL_1452 | |||||
| References | |||||
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| 1 | 1,3-Dialkyl-3-acyltriazenes, a novel class of antineoplastic alkylating agents. J Med Chem. 1990 Sep; 33(9):2579-83. | ||||
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