Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0I1VP) | |||||
|---|---|---|---|---|---|
| Name |
Nuclear factor-kappa B (NFKB)
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| Family | Other protein families (OPF) >> Transcription factor (TF) | ||||
| Organism |
Homo sapiens (Human)
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| UniProt ID | NFKB1_HUMAN | (click to find more protein-related data of this DBT) | |||
| NFKB2_HUMAN | (click to find more protein-related data of this DBT) | ||||
| TF65_HUMAN | (click to find more protein-related data of this DBT) | ||||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
|---|---|---|---|---|---|---|
| DIG Name: D&C red no. 30 | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
click to show the detail info of this DIG
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Colorant
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | EC50 = 122869 nM (estimated based on the structural similarity with CHEMBL1339303 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.776859504 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | NFKB1_HUMAN ; NFKB2_HUMAN ; TF65_HUMAN | |||||
| DIG Name: Tocopherol nicotinate | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
click to show the detail info of this DIG
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Antioxidant
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | EC50 = 189 nM (estimated based on the structural similarity with CHEMBL1328614 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.85492228 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | NFKB1_HUMAN ; NFKB2_HUMAN ; TF65_HUMAN | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | PubChem BioAssay data set. | ||||
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