Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0I5HA) | |||||
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| Name |
Monoamine oxidase (MAO)
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| Family | Oxidoreductase (ORase) >> CH-NH2 donor oxidoreductase (EC 1.4) | ||||
| Organism |
Homo sapiens (Human)
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| UniProt ID | AOFA_HUMAN | (click to find more protein-related data of this DBT) | |||
| AOFB_HUMAN | (click to find more protein-related data of this DBT) | ||||
| TTD ID | T62151 | (click to find more therapeutic target data of this DBT) | |||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Benzalkonium chloride | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Antimicrobial preservative; Penetration agent; Solubilizing agent; Surfactant
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 8200 nM (estimated based on the structural similarity with CHEMBL8695 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.97260274 | |||||
| Tested Species | Rattus norvegicus (Rat) | |||||
| UniProt ID | AOFA_RAT ; AOFB_RAT | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Synthesis and monoamine oxidase inhibitory activities of alpha-allenic amines in vivo and in vitro. Different activities of two enantiomeric allenes. J Med Chem. 1983 Jul; 26(7):1036-42. | ||||
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