Details of the Biological Target of DIG (DBT)

General Information of DBT (ID: ET0ID0A)
Name
Duodenal cancer HuTu80 cells (HuTu80)
Synonyms    Click to Show/Hide the Synonyms of This DBT
Human duodenal adenocarcinoma HuTu80 cells; HUTU 80; Hutu 80; HuTu-80; HUTU-80; Hutu-80; HUTU80; HuTu 80; Hutu80
Family Cell line (CELL)  >>  Duodenum cell line (DUOcel)
Organism
Homo sapiens (Human)
Cellosaurus ID CVCL_1301 (click to find more cell line data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Sodium desoxycholate Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Antioxidant; Surfactant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 82900 nM (estimated based on the structural similarity with CHEMBL406393 ) [1]
                   Structural Similarity Tanimoto coefficient = 1
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_1301
References
1 Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activity. Bioorg Med Chem Lett. 2017 Aug 15; 27(16):3755-3759.

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