Details of the Biological Target of DIG (DBT)

General Information of DBT (ID: ET0NT5C)
Name
Kidney HEK293 cells (HEK293)
Synonyms    Click to Show/Hide the Synonyms of This DBT
Human embryonic kidney HEK293 cells; Hek293; HEK-293; HEK/293; HEK 293; HEK;293; 293; 293 HEK; 293 Ad5; Human Embryonic Kidney 293
Family Cell line (CELL)  >>  Kidney cell line (KIDcel)
Organism
Homo sapiens (Human)
Cellosaurus ID CVCL_0045 (click to find more cell line data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Benzododecinium bromide Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Antimicrobial preservative
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 1 ug.mL-1 (tested by experiment) [1]
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0045
          DIG Name: Stearalkonium chloride Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Antimicrobial preservative; Surfactant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 1 ug.mL-1 (estimated based on the structural similarity with CHEMBL2355417 ) [1]
                   Structural Similarity Tanimoto coefficient = 0.974025974
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0045
References
1 Discovery of novel quaternary ammonium compounds based on quinuclidine-3-ol as new potential antimicrobial candidates. Eur J Med Chem. 2019 Feb 1; 163:626-635.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.