Details of the Biological Target of DIG (DBT)

General Information of DBT (ID: ET0QE6S)
Name
Melanoma MDA-MB-435 cells (MDA-MB-435)
Synonyms    Click to Show/Hide the Synonyms of This DBT
Human amelanotic melanoma MDA-MB-435 cells; MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435
Family Cell line (CELL)  >>  Skin cell line (SKIcel)
Organism
Homo sapiens (Human)
Cellosaurus ID CVCL_0417 (click to find more cell line data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Solvent orange 2 Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Colorant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 7120 nM (estimated based on the structural similarity with CHEMBL594474 ) [1]
                   Structural Similarity Tanimoto coefficient = 0.855172414
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0417
References
1 Synthesis of 2- and 17-substituted estrone analogs and their antiproliferative structure-activity relationships compared to 2-methoxyestradiol. Bioorg Med Chem. 2009 Oct 15; 17(20):7344-52.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.