Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F00329) | |||||
|---|---|---|---|---|---|
| Name |
Acetaminophen 500 mg tablet
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| Company |
Kareway Product
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| Active Pharmaceutical Ingredient (API) | Acetaminophen |
API Info
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| Anaesthesia | ICD-11: 8E22 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0T2PX | DIG Info | Lauryl sulfate | Emulsifying agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
|---|---|---|---|---|---|---|
| Cell line (CELL) | ||||||
| DBT Name: Fibrosarcoma WEHI-164 cells (WEHI-164) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Lauryl sulfate | |||||
| Biological Activity | IC50 = 15 ug.mL-1 (estimated based on the structural similarity with CHEMBL1162328 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.837837838 | |||||
| Tested Species | Mus musculus (Mouse) | |||||
| Cellosaurus ID | CVCL_2251 | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Novel bioactive sulfated alkene and alkanes from the mediterranean ascidian Halocynthia papillosa. J Nat Prod. 2000 Nov; 63(11):1590-2. | ||||
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