Details of the Drug Formulation (DFM)

General Information of DFM (ID: F12030)
Name
Levothroid 90 mg tablet
Company
Acella Pharmaceuticals; AvKARE; Preferred Pharamaceuticals
Active Pharmaceutical Ingredient (API) Levothroid API Info click to show the detail info of this API
Hypothyroidism ICD-11: 5A00 Approved
Drug Inactive Ingredient (DIGs)
DIG ID DIG Info DIG Name DIG Functional Class
E0F2PK DIG Info Calcium stearate lubricant
E0NN4I DIG Info Dextrin Binding agent ...
E07QET DIG Info Dextrose monohydrate Binding agent ...
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
      Cell line (CELL)
            DBT Name: Colon cancer Caco-2 cells (Caco-2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Dextrin
                    Biological Activity Inhibition ratio > 55 % (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
References
1 Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.

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