Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23615) | |||||
|---|---|---|---|---|---|
| Name |
Alprostadil 0.005mg/vial injectable
|
||||
| Company |
Auxilium Pharmaceuticals
|
||||
| Active Pharmaceutical Ingredient (API) | Alprostadil |
API Info
 click to show the detail info of this API
|
|||
| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0VD9B | DIG Info | Alfadex | Other agent | ||
| E0SJ4H | DIG Info | Beta-D-lactose | Diluent ... | ||
| E0T4TW | DIG Info | Sodium chloride | Diluent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
|---|---|---|---|---|---|---|
| Potential-driven transporter (PDT) | ||||||
| DBT Name: Norepinephrine transporter (NET) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
click to show the detail info of this DBT
|
|||||
| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Alfadex | |||||
| Biological Activity | Ki = 1260 nM (estimated based on the structural similarity with CHEMBL1629810 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.983606557 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | SC6A2_HUMAN | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | DrugMatrix in vitro pharmacology data. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.