Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23623) | |||||
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| Name |
Amikacin eq 250mg injectable
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| Company |
Teva Parenteral Medicines
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| Active Pharmaceutical Ingredient (API) | Amikacin |
API Info
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| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0NY5F | DIG Info | Sodium citrate dihydrate | Alkalizing agent ... | ||
| E0L2PN | DIG Info | Sodium hydroxide | Alkalizing agent | ||
| E0E9LJ | DIG Info | Sodium metabisulfite | Antimicrobial preservative ... | ||
| E0NV2K | DIG Info | Sulfuric acid | Acidulant | ||
| E0H2SC | DIG Info | Water | Solvent | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Lyase/isomerase/ligase (L/I/G) | ||||||
| DBT Name: Carbonic anhydrase V (CA5) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Sulfuric acid | |||||
| Biological Activity | Ki = 680 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CAH5A_HUMAN ; CAH5B_HUMAN | |||||
| References | |||||
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| 1 | Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorg Med Chem Lett. 2004 Nov 1; 14(21):5435-9. | ||||
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