Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23637) | |||||
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| Name |
Aztreonam 500mg/vial injectable
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| Company |
Bristol Myers Squibb
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| Active Pharmaceutical Ingredient (API) | Aztreonam |
API Info
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| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0V3RU | DIG Info | Arginine | Buffering agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| G-protein coupled receptor (GPCR) | ||||||
| DBT Name: GPCR33 receptor (GPRC6A) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Arginine | |||||
| Biological Activity | EC50 = 284000 nM (tested by experiment) | [1] | ||||
| Tested Species | Mus musculus (Mouse) | |||||
| UniProt ID | GPC6A_MOUSE | |||||
| References | |||||
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| 1 | A highly selective agonist for the metabotropic glutamate receptor mGluR2. Med Chem Comm. (2011) 2:1120-1124. | ||||
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