Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23638) | |||||
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| Name |
Aztreonam 75mg/vial for solution
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| Company |
Gilead
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| Active Pharmaceutical Ingredient (API) | Aztreonam |
API Info
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| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0XG3Z | DIG Info | Aminutrin | Buffering agent | ||
| E0T4TW | DIG Info | Sodium chloride | Diluent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Oxidoreductase (ORase) | ||||||
| DBT Name: Glutathione reductase (GSR) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Aminutrin | |||||
| Biological Activity | Ki = 54600 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | GSHR_HUMAN | |||||
| References | |||||
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| 1 | Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors. Bioorg Med Chem Lett. 2011 Sep 15; 21(18):5398-402. | ||||
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