Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23697) | |||||
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| Name |
Cromolyn 0.8mg/inh aerosol
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| Company |
King Pharms
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| Active Pharmaceutical Ingredient (API) | Cromolyn |
API Info
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| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0E1US | DIG Info | Dichlorodifluoromethane | Aerosol propellant | ||
| E0VT4B | DIG Info | Dichlorotetrafluoroethane | Aerosol propellant | ||
| E03JRW | DIG Info | Sorbitan trioleate | Dispersing agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Transferase (TFase) | ||||||
| DBT Name: Protein kinase C theta (PKC-Q) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Sorbitan trioleate | |||||
| Biological Activity | EC50 = 8670 nM (estimated based on the structural similarity with CHEMBL590047 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.901408451 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | KPCT_HUMAN | |||||
| References | |||||
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| 1 | Binding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C. Bioorg Med Chem. 2010 Feb 15; 18(4):1591-8. | ||||
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