Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F24243) | |||||
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| Name |
Etoposide Phosphate eq 100mg base/vial injectable
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| Company |
E.R. Squibb & Sons L.L.C.; H2-Pharma
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| Active Pharmaceutical Ingredient (API) | Etoposide |
API Info
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| Testicular carcinoma | ICD-11: 2C80 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0D2FK | DIG Info | Dextran | Lyophilization aid | ||
| E0M5SQ | DIG Info | Sodium citrate anhydrous | Alkalizing agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Lyase/isomerase/ligase (L/I/G) | ||||||
| DBT Name: Carbonic anhydrase IV (CA4) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Sodium citrate anhydrous | |||||
| Biological Activity | Ki = 99 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CAH4_HUMAN | |||||
| References | |||||
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| 1 | Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorg Med Chem Lett. 2005 Feb 1; 15(3):573-8. | ||||
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