Details of the Drug Formulation (DFM)
General Information of DFM (ID: F24320) | |||||
---|---|---|---|---|---|
Name |
Leucovorin Calcium 100mg/10ml lyophilized powder
|
||||
Company |
Sagent Pharmaceuticals
|
||||
Active Pharmaceutical Ingredient (API) | Leucovorin | API Info click to show the detail info of this API | |||
Colorectal cancer | ICD-11: 2B91 | Approved | |||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E0H0KW | DIG Info | Hydrochloric acid | Acidulant | ||
E0T4TW | DIG Info | Sodium chloride | Diluent ... | ||
E0L2PN | DIG Info | Sodium hydroxide | Alkalizing agent | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
---|---|---|---|---|---|---|
Lyase/isomerase/ligase (L/I/G) | ||||||
DBT Name: Carbonic anhydrase IV (CA4) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Hydrochloric acid | |||||
Biological Activity | Ki = 90000 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH4_HUMAN | |||||
DBT Name: Carbonic anhydrase V (CA5) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Hydrochloric acid | |||||
Biological Activity | Ki = 156 nM (tested by experiment) | [2] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH5A_HUMAN ; CAH5B_HUMAN | |||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.