Details of the Drug Formulation (DFM)
General Information of DFM (ID: F24351) | |||||
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Name |
Atropine 1mg/0.7ml solution
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Company |
Meridian Medical Technologies
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Active Pharmaceutical Ingredient (API) | Atropine | API Info click to show the detail info of this API | |||
Approved | |||||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E09QIG | DIG Info | Citric acid monohydrate | Acidulant ... | ||
E0R9NS | DIG Info | Nitrogen | Aerosol propellant ... | ||
E0T4TW | DIG Info | Sodium chloride | Diluent ... | ||
E0M5SQ | DIG Info | Sodium citrate anhydrous | Alkalizing agent ... | ||
E0H2SC | DIG Info | Water | Solvent | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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Lyase/isomerase/ligase (L/I/G) | ||||||
DBT Name: Carbonic anhydrase IV (CA4) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Sodium citrate anhydrous | |||||
Biological Activity | Ki = 99 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH4_HUMAN | |||||
References | |||||
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1 | Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorg Med Chem Lett. 2005 Feb 1; 15(3):573-8. | ||||
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