Drug General Information
Drug ID	D07ANY
Former ID	DNC004181
Drug Name	1H-1,2,3-benzotriazol-1-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526196]
Structure		Download 2D MOL 3D MOL
Formula	C6H6N4
Canonical SMILES	C1=CC=C2C(=C1)N=NN2N
InChI	1S/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H2
InChIKey	JCXKHYLLVKZPKE-UHFFFAOYSA-N
PubChem Compound ID	1367
Target and Pathway
Target(s)	Cytochrome P450 3A4	Target Info	Inhibitor	[526196]
	Cytochrome P450 2D6	Target Info	Inhibitor	[526196]
KEGG Pathway	Steroid hormone biosynthesis
	Linoleic acid metabolism
	Retinol metabolism
	Metabolism of xenobiotics by cytochrome P450
	Drug metabolism - cytochrome P450
	Drug metabolism - other enzymes
	Metabolic pathways
	Bile secretion
	Chemical carcinogenesishsa00980:Metabolism of xenobiotics by cytochrome P450
	Serotonergic synapse
PathWhiz Pathway	Caffeine Metabolism
	Retinol Metabolism
Reactome	Xenobiotics
	Aflatoxin activation and detoxificationR-HSA-211981:Xenobiotics
WikiPathways	Metapathway biotransformation
	Aflatoxin B1 metabolism
	Estrogen metabolism
	Benzo(a)pyrene metabolism
	Tamoxifen metabolism
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	Farnesoid X Receptor Pathway
	Vitamin D Receptor Pathway
	Felbamate Metabolism
	Lidocaine metabolism
	Nifedipine Activity
	Colchicine Metabolic Pathway
	Irinotecan Pathway
	Drug Induction of Bile Acid Pathway
	Fatty Acid Omega Oxidation
	Codeine and Morphine MetabolismWP702:Metapathway biotransformation
	Aripiprazole Metabolic Pathway
	Codeine and Morphine Metabolism
References
Ref 526196	Bioorg Med Chem Lett. 2001 Dec 3;11(23):2993-5.Discovery of a N'-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor.
Ref 526196	Bioorg Med Chem Lett. 2001 Dec 3;11(23):2993-5.Discovery of a N'-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor.

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