Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00350) | |||||
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Name |
Lanthanum carbonate
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Synonyms |
Click to Show/Hide the Synonyms of This API
Lanthanum Carbonate; 587-26-8; Lanthanum sesquicarbonate; Carbonic acid, lanthanum(3+) salt (3:2); UNII-0M78EU4V9H; lanthanum(3+);tricarbonate; 0M78EU4V9H; Dilanthanum tricarbonate; Carbonic acid,lanthanum(3+) salt (3:2), octahydrate (8CI,9CI); Lanthanum(3 ) carbonate; EINECS 209-599-5; HSDB 7758; lanthanum(iii) carbonate; Lanthanum(3+) carbonate; Lanthanum Carbonate powder; ACMC-1BB7U; C3La2O9; Lanthanum (III) carbonate; EC 209-599-5; lanthanum carbonate (2:3); Lanthanum carbonate anhydrous; DTXSID30890512; DB06792; Q421317; Carbonic acid,lanthanum(3+) salt (3:2), hydrate (9CI)
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Clinical Status |
Approved
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Disease Indication | Hyperphosphatemia | ICD-11: 5C64 | [1] | ||
PubChem CID | |||||
Formula |
C3La2O9
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Canonical SMILES |
C(=O)([O-])[O-].C(=O)([O-])[O-].C(=O)([O-])[O-].[La+3].[La+3]
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InChI |
1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6
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InChIKey |
NZPIUJUFIFZSPW-UHFFFAOYSA-H
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=168924"></iframe>
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3D MOL is unavailable | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 457.84 | Topological Polar Surface Area | 190 | |
XlogP | N.A. | Complexity | 18.8 | ||
Heavy Atom Count | 14 | Rotatable Bond Count | 0 | ||
Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 9 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Lanthanum carbonate 1000 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Talc; Silicon dioxide; Dextrates; Hydroxypropyl cellulose
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Dosage Form | Chewable Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Silicon dioxide; Dextrates
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Dosage Form | Chewable Tablet | |||||
Company | Prasco; Shire | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Lanthanum carbonate 500 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Talc; Silicon dioxide; Dextrates; Hydroxypropyl cellulose
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Dosage Form | Chewable Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Silicon dioxide; Dextrates
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Dosage Form | Chewable Tablet | |||||
Company | Avera McKennan Hospital; Cardinal Health; Prasco; Shire | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Lanthanum carbonate 750 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Talc; Silicon dioxide; Dextrates; Hydroxypropyl cellulose
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Dosage Form | Chewable Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Silicon dioxide; Dextrates
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Dosage Form | Chewable Tablet | |||||
Company | Prasco; Shire | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [2] | |||
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