General Information of API (ID: D01482)
Name
Thiotepa
Synonyms    Click to Show/Hide the Synonyms of This API
thiotepa; THIO-TEPA; 52-24-4; Triethylenethiophosphoramide; Thiophosphamide; Thioplex; Tiofosfamid; Tiofosyl; Thiofozil; Tespamin; Girostan; Oncotepa; Tespamine; Tiofozil; Stepa; Oncotiotepa; Thiotef; Tifosyl; Oncothio-tepa; TESPA; Tio-tef; Thio-Tep; Tri(aziridin-1-yl)phosphine sulfide; TSPA; Thio-tepa S; Ledertepa; Thiotriethylenephosphoramide; TIO TEF; Tris(1-aziridinyl)phosphine sulfide; 1,1',1''-phosphorothioyltriaziridine; N,N',N''-Triethylenethiophosphoramide; Triethylene thiophosphoramide; Triaziridinylphosphine sulfide; NSC-6396; Triethylenethiophosphorotriamide; Tris(ethylenimino)thiophosphate; CBC 806495; Phosphorothioic acid triethylenetriamide; Phosphine sulfide, tris(1-aziridinyl)-; Tri(ethyleneimino)thiophosphoramide; Aziridine, 1,1',1''-phosphinothioylidynetris-; NCI-C01649; NSC 6396; SK 6882; Tris(aziridinyl)phosphine sulfide; Tri-1-aziridinylphosphine sulfide; Tris(1-aziridinyl)phosphine sulphide; N,N',N''-Triethylenethiophosphamide; UNII-905Z5W3GKH; N,N',N''-Triethylenethiophosphortriamide; NSC6396; 1,1',1''-Phosphinothioylidynetrisaziridine; N,N',N''-Triethylenephosphorothioic triamide; N,N',N''-Tri-1,2-ethanediylthiophosphoramide; MFCD00145452; Thiophosphoramide, N,N',N''-tri-1,2-ethanediyl-; N,N',N''-Tri-1,2-ethanediylphosphorothioic triamide; MLS001333083; MLS003389372; 905Z5W3GKH; CHEBI:9570; Phosphorothioic triamide, N,N',N''-tri-1,2-ethanediyl-; AI 3-24916; Phosphorothioic triamide, N,N',N''-triethylene-; tepadina; NCGC00095042-04; NCGC00095042-06; Thiophosphamidum; DSSTox_CID_1339; DSSTox_RID_76093; DSSTox_GSID_21339; C6H12N3PS; Thiotepum; Tiotepa; Thiotepum [INN-Latin]; Tiotepa [INN-Spanish]; CAS-52-24-4; Phosphoric tri(ethyleneamide); SMR000058542; CCRIS 586; HSDB 3258; AI3-24916; SR-05000001855; EINECS 200-135-7; BRN 0145978; WR-45312; Thiotepa [USP:INN:BAN:JAN]; Tepadina (TN); Thioplex (TN); Rethio (TN); Thiotepa (Thioplex); Spectrum_001689; WR 45312; Thiophosphoramide, N,N',N''-triethylene-; Spectrum2_001557; Spectrum3_001594; Spectrum4_000208; Spectrum5_001641; tris(aziridin-1-yl)-thioxo-$l^{5}-phosphane; CHEMBL671; Thioplex (TN) (Immunex); Tris(aziridinyl)-phosphine sulfide (thio-tepa); SCHEMBL4760; Thiotepa (JAN/USP/INN); Thio-TEPA, 98%, solid; BSPBio_003188; KBioGR_000815; KBioSS_002169; 4-20-00-00052 (Beilstein Handbook Reference); MLS001333084; MLS002207150; MLS006009972; ARONIS24177; BIDD:GT0127; DivK1c_000817; SPECTRUM1503324; SPBio_001434; GTPL7622; DTXSID0021339; HMS502I19; KBio1_000817; KBio2_002169; KBio2_004737; KBio2_007305; KBio3_002688; N,N''-Triethylenethiophosphamide; AOB5373; NINDS_000817; HMS1922A14; HMS2093E05; HMS2232P17; HMS3372D10; N,N''-Triethylenethiophosphoramide; Pharmakon1600-01503324; Tri(1-aziridinyl)phosphine sulfide; AMY33389; BCP04110; ZINC1530867; Tox21_111399; Tox21_400065; ANW-58232; BDBM50418086; CCG-39776; NSC758455; RW2156; s1775; AKOS005267118; CS-3119; DB04572; GC10080; MCULE-5478761622; NSC-758455; 1,1''-Phosphinothioylidynetrisaziridine; IDI1_000817; Thiophosphoramide,N',N'' -triethylene-; N,N',N'''-Triethylenethiophosphhoramide; NCGC00095042-01; NCGC00095042-02; NCGC00095042-03; NCGC00095042-05; NCGC00095042-07; NCGC00095042-08; NCGC00095042-09; AS-16885; HY-17574; N,N''-Triethylenephosphorothioic triamide; NCI60_013117; SBI-0051814.P002; tris(1-aziridinyl)-sulfanylidenephosphorane; AB0006704; Aziridine,1',1''-phosphinothioylidynetris-; N,N''-Tri-1,2-ethanediylthiophosphoramide; Phosphorothioic triamide,N',N''-triethylene; Thiophosphoramide, N,N',N'' -triethylene-; tris(aziridin-1-yl)-lambda5-phosphanethione; FT-0600281; tris(aziridin-1-yl)-$l^{5}-phosphanethione; tris(aziridin-1-yl)-sulfanylidenephosphorane; WLN: T3NTJ APS&- AT3NTJ&- AT3NTJ; Y0223; 1-[Di(1-aziridinyl)phosphorothioyl]aziridine #; C07641; D00583; Phosphorothioic triamide, N,N',N''-triethylene; Thiophosphoramide,N',N''-tri-1,2-ethanediyl-; Z-0841; 24126-EP2272827A1; 24126-EP2272832A1; 24126-EP2275420A1; 24126-EP2280012A2; 24126-EP2292615A1; 24126-EP2295055A2; 24126-EP2295416A2; 24126-EP2295426A1; 24126-EP2295427A1; 24126-EP2298748A2; 24126-EP2298764A1; 24126-EP2298765A1; 24126-EP2298768A1; 24126-EP2298778A1; 24126-EP2301928A1; 24126-EP2305642A2; 24126-EP2308833A2; 24126-EP2311453A1; 24126-EP2314590A1; AB00052346-06; AB00052346_07; 145T452; A828998; N,N''-Tri-1,2-ethanediylphosphorothioic triamide; Q416507; Q-201826; SR-05000001855-1; SR-05000001855-5; tris(aziridin-1-yl)-sulfanylidene-$l^{5}-phosphane; AZIRIDINE,1,1',1''-PHOSPHINOTHIOYLIDYNETRIS-; BRD-K09631521-001-05-7; Phosphorothioic triamide,N',N''-tri-1,2-ethanediyl-; Z2574360269; Thiotepa, United States Pharmacopeia (USP) Reference Standard; 1631739-26-8
Clinical Status
Approved
PubChem CID
5453
Formula
C6H12N3PS
Canonical SMILES
C1CN1P(=S)(N2CC2)N3CC3
InChI
1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2
InChIKey
FOCVUCIESVLUNU-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5453"></iframe>
3D MOL is unavailable 2D MOL
Physicochemical Properties Molecular Weight 189.22 Topological Polar Surface Area 41.1
XlogP 0.5 Complexity 194
Heavy Atom Count 11 Rotatable Bond Count 3
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 4
Full List of Drug Formulations (DFMs) Containing This API
          Thiotepa 15mg lyophilized powder Click to Show/Hide the Full List of Formulation(s):          1 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Water
                   Dosage Form Lyophilized Powder
                   Company Gland Pharma Limited

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