Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00207) | |||||
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Name |
Methamphetamine
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Synonyms |
Click to Show/Hide the Synonyms of This API
Metamfetamine; d-Methamphetamine; d-Deoxyephedrine; d-Desoxyephedrine; Metamphetamine; d-N-Methylamphetamine; d-Methylamphetamine; Methylamphetamine; d-Phenylisopropylmethylamine; N-Methylamphetamine; (S)-Methamphetamine; Norodin; (+)-Methylamphetamine; d-(S)-Methamphetamine; D-1-Phenyl-2-methylaminopropane; Desyphed; (+)-N-Methylamphetamine; (S)-Methylamphetamine; (+)-(S)-Deoxyephedrine; Methyl-beta-phenylisopropylamine; 1-Phenyl-2-methylaminopropane; (S)-(+)-Deoxyephedrine; Metamfetamina; Metamfetaminum; (+)-methamphetamine; 537-46-2; Metanfetamina; S-(+)-Methamphetamine; (S)-N,alpha-Dimethylbenzeneethanamine; (2S)-N-methyl-1-phenylpropan-2-amine; D-N,alpha-dimethylphenethylamine; Metamfetaminum [INN-Latin]; Metamfetamina [INN-Spanish]; Metanfetamina [INN-Spanish]; Methamphetaminum [INN-Latin]; (+)-2-(N-Methylamino)-1-phenylpropane; Meth; Metamfetamine [INN]; N-Methyl-beta-phenylisopropylamine; 1-Phenyl-2-methylamino-propan [German]; (+)-N,alpha-Dimethylphenethylamine; d-1-Phenyl-2-methylaminopropan [German]; (+)-N,alpha-Dimethyl-beta-phenylethylamine; D-1-Phenyl-2-methylaminopropan; 2S-(+)-Methamphetamine; dextromethamphetamine; (S)-(+)-Methamphetamine; (+)-(S)-N-alpha-Dimethylphenethylamine; N-Methyl-beta-phenylisopropylamin [German]; NSC 25115; (S)-N,alpha-Dimethylbenzeneethanoamine; UNII-44RAL3456C; CHEBI:6809; (S)-(+)-N,alpha,dimethylphenethylamine; Metamfetamine (INN); (alphaS)-N,alpha-dimethylbenzeneethanamine; Benzeneethanamine, N,alpha-dimethyl-, (S)-; Methyl-.beta.-phenylisopropylamine; d-N,.alpha.-Dimethylphenethylamine; Stimulex; Speed; 44RAL3456C; Benzeneethanamine, N,alpha-dimethyl-, (alphaS)-; 1-Phenyl-2-methylamino-propan; NSC-25115; N-Methyl-beta-phenylisopropylamin; Crank; Methamphetaminum; Methamphetaminum [JP]; Crystal Meth; Metamfetaminum [Latin]; Metanfetamina [Spanish]; Meth (Street Name); ICE [Street Name]; Crank [Street Name]; Speed [Street Name]; Crystal Meth [Street Name]; HSDB 3359; N-Methyl-1-phenyl-2-propanamine; (+ )-Methylamphetamine; EINECS 208-668-7; Phenethylamine, N,alpha-dimethyl-, (+)-; Benzeneethanamine, N,alpha-dimethyl-, (+)-; DEA No. 1105; B40; Benzeneethanamine, N,.alpha.-dimethyl-, (S)-; Methamphetamine, its salts, isomers, and salts of its isomers; Phenethylamine, N,.alpha.-dimethyl-, (S)-(+)-; Epitope ID:178090; intra-venous methamphetamine; Phenethylamine, N,alpha-dimethyl-, (S)-(+)-; Benzeneethanamine,.alpha.-dimethyl-, (S)-; d-N,a-dimethylphenethylamine; SCHEMBL42615; Phenethylamine,.alpha.-dimethyl-, (S)-(+)-; CHEMBL1201201; DTXSID8037128; WLN: 1MY1&1R -D; N,I+/--Dimethyl-phenethyl amine; Desyphed hydrochloride (Salt/Mix); NSC25115; ZINC6021043; N-Methyl-1-phenyl-2-propanamine #; BDBM50359499; PDSP1_001404; PDSP1_001405; PDSP2_001388; PDSP2_001389; (+)-N,.alpha.-Dimethylphenethylamine; (S)-N-methyl-1-phenylpropan-2-amine; DB01577; J6.362B; Desoxyephedrine hydrochloride (Salt/Mix); methyl[(2S)-1-phenylpropan-2-yl]amine; Phenethylamine,.alpha.-dimethyl-, (+)-; (+)-(S)-N-.alpha.-Dimethylphenethylamine; Benzeneethanamine,.alpha.-dimethyl-, (+)-; Phenethylamine, N,.alpha.-dimethyl-, (+)-; Benzeneethanamine, N,.alpha.-dimethyl-, (+)-; C07164; D08187; (+)-N,.alpha.-Dimethyl-.beta.-phenylethylamine; Q191924; Phenethylamine, N,alpha-dimethyl-, (S)-(+)- (8CI); Benzeneethanamine, N,alpha-dimethyl-, (alphaS)- (9CI); UNII-13ZT6YG5SD component MYWUZJCMWCOHBA-VIFPVBQESA-N; (+)-N,.alpha.-Dimethylphenethylamine hydrochloride (Salt/Mix); S(+)-Methamphetamine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material
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Clinical Status |
Approved
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Disease Indication | Attention deficit hyperactivity disorder | ICD-11: 6A05 | [1] | ||
PubChem CID | |||||
Formula |
C10H15N
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Canonical SMILES |
C[C@@H](CC1=CC=CC=C1)NC
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InChI |
1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1
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InChIKey |
MYWUZJCMWCOHBA-VIFPVBQESA-N
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=10836"></iframe>
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3D MOL | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 149.23 | Topological Polar Surface Area | 12 | |
XlogP | 2.1 | Complexity | 95 | ||
Heavy Atom Count | 11 | Rotatable Bond Count | 3 | ||
Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 1 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Methamphetamine 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose; Aminobenzoate sodium; Talc; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Lundbeck Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Aminobenzoate sodium | DIG Info | Carbonic anhydrase II (Ki = 8130 nM) | [3] | |||
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