Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00545)
Name	Potassium iodide
Synonyms	Click to Show/Hide the Synonyms of This API potassium iodide; 7681-11-0; Potassium iodide (KI); Kali iodide; Thyro-Block; Potassium monoiodide; Knollide; Asmofug E; Potassium diiodide; Dipotassium diiodide; Kaliumiodid; potassium;iodide; Potassium iodide (K2I2); Potassium iodide (K(I2)); potassiumiodide; UNII-1C4QK22F9J; MFCD00011405; 1C4QK22F9J; CHEBI:8346; NSC-77362; Thyroshield; Joptone; Potide; Kalii iodidum; Potassium iodide solution; Iodure de potassium; Tripotassium triiodide; Caswell No. 694; iodopotassium; Thyrosafe; Kalium iodatum; potassium-iodide; Iodine Solution, 0.1N (N/10); Potassium iodide (K3I3); Potassium iodide, 99+%, ACS reagent; Potassium iodide, 99+%, for analysis; Potassium iodide, 99%, for biochemistry; HSDB 5040; Potassium iodide, 99%, extra pure, briquettes; EINECS 231-659-4; NSC 77362; EPA Pesticide Chemical Code 075701; Kaliumjodid; potasium iodide; potassium iodid; Potassium iodide [USP:JAN]; Potassium iodide, 99.995%, (trace metal basis), extra pure; AI3-52931; CCRIS 8168; Potassium salt of hydriodic acid; Thyroblock (TN); potassium iodide ts; Potassium Iodide AR; Gold etchant, standard; Potassium Iodide,(S); ACMC-1BDBB; Nesslers Reagent Solution; Potassium Iodide USP/FCC; Potassium iodide ACS grade; WLN: KA I; EC 231-659-4; Potassium iodide, ultra dry; CHEMBL1141; DSSTox_CID_14836; DSSTox_RID_79208; DSSTox_GSID_34836; Potassium Iodide Neutral ACS; Potassium iodide, ACS reagent; Potassium iodide (JP17/USP); DTXSID7034836; Potassium iodide, LR, >=99%; HMS3651G04; CS-B1801; K I (H2 O)2; NSC77362; Potassium iodide, AR, >=99.8%; Tox21_301293; ANW-46028; Mercuric and potassium iodide solution; AKOS015833375; CCG-266323; DB06715; LS41972; Potassium iodide, BioXtra, >=99.0%; NCGC00257542-01; Potassium iodide solution, 15 % (w/v); Potassium iodide, ReagentPlus(R), 99%; CAS-7681-11-0; Potassium iodide, Vetec(TM) reagent grade; Potassium iodide, ACS reagent, >=99.0%; Potassium iodide, plant cell culture tested; FT-0645116; Potassium iodide, 99.999% (metals basis); SW219147-1; Potassium iodide, BioUltra, >=99.5% (AT); Potassium iodide, tested according to Ph.Eur.; Potassium iodide, Trace metals grade 99.99%; C08219; D01016; Potassium iodide, SAJ first grade, >=99.5%; Y-9233; AB01274864-01; AB01568251_01; Potassium iodide, >=99.99% trace metals basis; Potassium iodide, JIS special grade, >=99.5%; Potassium iodide, purum p.a., >=99.0% (AT); Q121874; Potassium iodide, puriss. p.a., ACS reagent, >=99.0% (AT); Potassium iodide, suitable for oxidant determination, >=99.5%; Potassium iodide, anhydrous, beads, -10 mesh, 99.998% trace metals basis; Potassium iodide, puriss. p.a., reag. ISO, reag. Ph. Eur., >=99.5%; Potassium iodide, United States Pharmacopeia (USP) Reference Standard; Potassium iodide, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%; Potassium iodide, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%
Clinical Status	Approved
Disease Indication	Thyrotoxicosis		ICD-11: 5A02	[1]
PubChem CID	4875
Formula	IK
Canonical SMILES	[K+].[I-]
InChI	1S/HI.K/h1H;/q;+1/p-1
InChIKey	NLKNQRATVPKPDG-UHFFFAOYSA-M
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4875"></iframe>
Structure	3D MOL is unavailable		2D MOL
Physicochemical Properties	Molecular Weight	166.003	Topological Polar Surface Area	0
	XlogP	N.A.	Complexity	2
	Heavy Atom Count	2	Rotatable Bond Count	0
	Hydrogen Bond Donor Count	0	Hydrogen Bond Acceptor Count	1

Full List of Drug Formulations (DFMs) Containing This API
Potassium iodide 130 mg tablet			Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Sodium thiosulfate anhydrous; Silicon dioxide; Cellulose, microcrystalline
Dosage Form	Oral Tablet
Company	Anbex
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[2]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[2]
Potassium iodide 65 mg tablet			Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Sodium thiosulfate anhydrous; Silicon dioxide; Cellulose, microcrystalline
Dosage Form	Oral Tablet
Company	Anbex
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[2]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[2]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Cellulose, microcrystalline
Dosage Form	Oral Tablet
Company	Recipharm AB
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[2]

References
1	FDA label for approved loxapine from the official website of the U.S. Food and Drug Administration.
2	Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.

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