Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00640)
Name
Succimer
Synonyms    Click to Show/Hide the Synonyms of This API
Succimer; meso-2,3-Dimercaptosuccinic acid; 304-55-2; meso-Dimercaptosuccinic acid; Dim-sa; (2R,3S)-rel-2,3-Dimercaptosuccinic acid; Succimero; Succimerum; Dimercaptosuccinic acid; Chemet; Butanedioic acid, 2,3-dimercapto-, (2R,3S)-rel-; (R*,S*)-2,3-Dimercaptobutanedioic acid; UNII-DX1U2629QE; Ro 1-7977; MFCD00064799; DX1U2629QE; CHEBI:63623; meso-2,3-Dimercaptobernsteinsaeure; meso-2,3-Dimercaptosuccinic acid;; (2R,3S)-2,3-disulfanylsuccinic acid; Butanedioic acid, 2,3-dimercapto-, (R*,S*)-; Succimerum [INN-Latin]; Succimero [INN-Spanish]; (2R,3S)-2,3-dimercaptosuccinic acid; meso-2,3-Dimercaptosuccinic acid, 98%; Succinic acid, 2,3-dimercapto-, meso-; Succimer [USAN:INN:BAN]; (3S,2R)-2,3-disulfanylbutanedioic acid; HSDB 6783; 3-03-00-01033 (Beilstein Handbook Reference); EINECS 206-155-2; 2,3-bis-sulfanylbutanedioic acid; BRN 1725150; Chemet (TN); Succimer (USAN/INN); (2R,3S)-rel-2,3-Dimercaptobutanedioic acid; SCHEMBL14941; SPECTRUM1505007; CHEMBL1201073; DTXSID1023601; HY-B1768; MESO-2,3-DIMERCAPTOSUCCINIC; ZINC3831475; SBB065802; AKOS015892684; AC-1366; CCG-214189; DB00566; DS-7410; meso-2,3-Dimercaptosuccinic acid, ~98%; CS-0013797; ST51007322; A17093; C07598; D00572; 304D552; Q423814; Q-201748; BRD-K88701661-001-01-1; UNII-4S9JU7XF01 component ACTRVOBWPAIOHC-XIXRPRMCSA-N
Clinical Status
Approved
Disease Indication Lead poisoning ICD-11: 8D43 [1]
PubChem CID
2724354
Formula
C4H6O4S2
Canonical SMILES
[C@@H]([C@@H](C(=O)O)S)(C(=O)O)S
InChI
1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+
InChIKey
ACTRVOBWPAIOHC-XIXRPRMCSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2724354"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 182.2 Topological Polar Surface Area 76.6
XlogP 0.1 Complexity 139
Heavy Atom Count 10 Rotatable Bond Count 3
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6
Full List of Drug Formulations (DFMs) Containing This API
          Succimer 100 mg capsule Click to Show/Hide the Full List of Formulation(s):          1 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Ferric oxide red; Sucrose; Titanium dioxide; Gelatin; Povidones; Sodium starch glycolate type a potato; Starch, corn
                   Dosage Form Oral Capsule
                   Company Recordati Rare Diseases
References
1 FDA label for approved succimer from the official website of the U.S. Food and Drug Administration.

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