General Information of DBT (ID: ET02KFG)
Name
Muscarinic receptor (CHRM)
Family G-protein coupled receptor (GPCR)  >>  G-protein coupled rhodopsin receptor (GPCR-A)
Organism
Homo sapiens (Human)
UniProt ID ACM1_HUMAN (click to find more protein-related data of this DBT)
ACM2_HUMAN (click to find more protein-related data of this DBT)
ACM3_HUMAN (click to find more protein-related data of this DBT)
ACM4_HUMAN (click to find more protein-related data of this DBT)
ACM5_HUMAN (click to find more protein-related data of this DBT)
TTD ID T09130 (click to find more therapeutic target data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Methylpyrrolidone Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Penetration agent; Solubilizing agent; Solvent
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 13 nM (estimated based on the structural similarity with CHEMBL23957 ) [1]
                   Structural Similarity Tanimoto coefficient = 0.87804878
                   Tested Species Rattus norvegicus (Rat)
                   UniProt ID ACM1_RAT ; ACM2_RAT ; ACM3_RAT ; ACM4_RAT ; ACM5_RAT
References
1 Substituent variation in azabicyclic triazole- and tetrazole-based muscarinic receptor ligands. J Med Chem. 1992 Jun 26; 35(13):2392-406.

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