Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET02VYA) | |||||
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| Name |
Lymphoma P388/ADR cells (P388/ADR)
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| Synonyms |
Click to Show/Hide the Synonyms of This DBT
Mouse lymphoma P388/ADR cells
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| Family | Cell line (CELL) >> Blood cell line (BLOcel) | ||||
| Organism |
Mus musculus (Mouse)
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| Cellosaurus ID | CVCL_IZ75 | (click to find more cell line data of this DBT) | |||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Isopropyl alcohol | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Antimicrobial preservative; Solvent
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 0.22 uM (estimated based on the structural similarity with CHEMBL545 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.789473684 | |||||
| Tested Species | Mus musculus (Mouse) | |||||
| Cellosaurus ID | CVCL_IZ75 | |||||
| References | |||||
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| 1 | Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22. | ||||
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