General Information of DBT (ID: ET0CE2Y)
Name
Ovarian cancer A2780 cells (A2780)
Synonyms    Click to Show/Hide the Synonyms of This DBT
Human ovarian carcinoma A2780 cells; A-2780; A2780S
Family Cell line (CELL)  >>  Ovary cell line (OVAcel)
Organism
Homo sapiens (Human)
Cellosaurus ID CVCL_0134 (click to find more cell line data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Raffinose Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Lyophilization aid
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 60 nM (estimated based on the structural similarity with CHEMBL1744450 ) [1]
                   Structural Similarity Tanimoto coefficient = 1
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0134
          DIG Name: Triethanolamine lauryl sulfate Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Complexing agent; Emulsifying agent; Surfactant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 10060 nM (estimated based on the structural similarity with CHEMBL3408657 ) [2]
                   Structural Similarity Tanimoto coefficient = 0.754716981
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0134
References
1 Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing. Bioorg Med Chem. 2010 Mar 1; 18(5):1844-53.
2 Synthesis of structural analogues of hexadecylphosphocholine and their antineoplastic, antimicrobial and amoebicidal activity. Eur J Med Chem. 2015 Mar 26; 93:263-73.

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