Details of the Biological Target of DIG (DBT)

General Information of DBT (ID: ET0F3PC)
Name
Colon cancer SW620 cells (SW620)
Synonyms    Click to Show/Hide the Synonyms of This DBT
Human colon adenocarcinoma SW620 cells; SW-620; SW 620; SW.620
Family Cell line (CELL)  >>  Colon cell line (COLcel)
Organism
Homo sapiens (Human)
Cellosaurus ID CVCL_0547 (click to find more cell line data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Calcium ascorbate anhydrous Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Antioxidant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 > 100000 nM (estimated based on the structural similarity with CHEMBL196 ) [1]
                   Structural Similarity Tanimoto coefficient = 1
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0547
          DIG Name: Pigment yellow 3 Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Colorant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 450 nM (estimated based on the structural similarity with CHEMBL1807120 ) [2]
                   Structural Similarity Tanimoto coefficient = 0.80141844
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0547
References
1 Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives. Eur J Med Chem. 2019 Dec 15; 184:111739.
2 Synthesis and biological evaluation of 4-nitro-substituted 1,3-diaryltriazenes as a novel class of potent antitumor agents. Eur J Med Chem. 2011 Jul; 46(7):2971-83.

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