Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0HH1S) | |||||
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| Name |
Proconvertin-TF complex (F7-F3)
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| Synonyms |
Click to Show/Hide the Synonyms of This DBT
Coagulation factor VII complexed with CD142; Eptacog alfa complexed with Coagulation factor III; Proconvertin complexed with TF; SPCA complexed with Thromboplastin; Serum prothrombin conversion accelerator complexed with Tissue factor
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| Family | Hydrolase (HDase) >> Peptidase (EC 3.4) | ||||
| Organism |
Homo sapiens (Human)
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| UniProt ID | FA7_HUMAN | (click to find more protein-related data of this DBT) | |||
| TF_HUMAN | (click to find more protein-related data of this DBT) | ||||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Oleic acid | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Emulsifying agent; Penetration agent; Solubilizing agent
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 80000 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | FA7_HUMAN ; TF_HUMAN | |||||
| DIG Name: Linoleic acid | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
click to show the detail info of this DIG
|
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Emulsifying agent; Penetration agent; Solubilizing agent
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 41000 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | FA7_HUMAN ; TF_HUMAN | |||||
| References | |||||
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| 1 | Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex. J Nat Prod. 1998 Nov; 61(11):1352-5. | ||||
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