Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0YR2F) | |||||
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| Name |
Microglial BV-2 cells (BV-2)
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| Synonyms |
Click to Show/Hide the Synonyms of This DBT
Mouse microglial BV-2 cells; BV2
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| Family | Cell line (CELL) >> Brain cell line (BRAcel) | ||||
| Organism |
Mus musculus (Mouse)
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| Cellosaurus ID | CVCL_0182 | (click to find more cell line data of this DBT) | |||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Sodium stearate | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
Emulsifying agent; Gelling agent; Glidant; Modified-release agent; Stiffening agent; lubricant
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 > 100000 nM (estimated based on the structural similarity with CHEMBL464787 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 1 | |||||
| Tested Species | Mus musculus (Mouse) | |||||
| Cellosaurus ID | CVCL_0182 | |||||
| References | |||||
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| 1 | Natural neuro-inflammatory inhibitors from Caragana turfanensis. Bioorg Med Chem Lett. 2017 Oct 15; 27(20):4765-4769. | ||||
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