Details of the Biological Target of DIG (DBT)

General Information of DBT (ID: ET0Z4JY)
Name
Colon cancer HT-29 cells (HT-29)
Synonyms    Click to Show/Hide the Synonyms of This DBT
Human colon adenocarcinoma HT-29 cells; HT 29; HT29
Family Cell line (CELL)  >>  Colon cell line (COLcel)
Organism
Homo sapiens (Human)
Cellosaurus ID CVCL_0320 (click to find more cell line data of this DBT)
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT
          DIG Name: Stearic acid Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Emulsifying agent; Solubilizing agent; Viscosity-controlling agent; lubricant
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 > 200000 nM (tested by experiment) [1]
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0320
          DIG Name: Dimethoxane Click to Show/Hide
             Detailed Information DIG Info click to show the detail info of this DIG
             Functional Class    Click to Show/Hide the Functional Class of This DIG
Antimicrobial preservative
             Experiment for Assessing the Biological Activity of This DIG on the Studied DBT
                   Biological Activity IC50 = 332000 nM (estimated based on the structural similarity with CHEMBL179520 ) [2]
                   Structural Similarity Tanimoto coefficient = 0.794871795
                   Tested Species Homo sapiens (Human)
                   Cellosaurus ID CVCL_0320
References
1 Liposomal formulation of retinoids designed for enzyme triggered release. J Med Chem. 2010 May 13; 53(9):3782-92.
2 The role of intracellularly released formaldehyde and butyric acid in the anticancer activity of acyloxyalkyl esters. J Med Chem. 2005 Feb 24; 48(4):1042-54.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.