Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F12652) | |||||
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| Name |
Omega-3 acid ethyl ester 1000 mg capsule
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| Company |
GlaxoSmithKline
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| Active Pharmaceutical Ingredient (API) | Omega-3 acid ethyl ester |
API Info
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| Hypertriglyceridaemia | ICD-11: 5C80 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0LT2O | DIG Info | Alpha-tocopherol | Antimicrobial preservative ... | ||
| E06WYP | DIG Info | Glycerin | Antimicrobial preservative ... | ||
| E0H2SC | DIG Info | Water | Solvent | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Transferase (TFase) | ||||||
| DBT Name: Glutathione S-transferase P (GSTP1) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Alpha-tocopherol | |||||
| Biological Activity | IC50 = 500 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | GSTP1_HUMAN | |||||
| References | |||||
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| 1 | Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem. 2018 Sep 13; 61(17):7448-7470. | ||||
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