Details of the Drug Formulation (DFM)
General Information of DFM (ID: F12659) | |||||
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Name |
Omega-3 acid ethyl ester 1200 mg capsule
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Company |
Trygg Pharma
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Active Pharmaceutical Ingredient (API) | Omega-3 acid ethyl ester | API Info click to show the detail info of this API | |||
Hypertriglyceridaemia | ICD-11: 5C80 | Approved | |||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E0LT2O | DIG Info | Alpha-tocopherol | Antimicrobial preservative ... | ||
E06WYP | DIG Info | Glycerin | Antimicrobial preservative ... | ||
E0H2SC | DIG Info | Water | Solvent | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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Transferase (TFase) | ||||||
DBT Name: Glutathione S-transferase P (GSTP1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Alpha-tocopherol | |||||
Biological Activity | IC50 = 500 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | GSTP1_HUMAN | |||||
References | |||||
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1 | Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem. 2018 Sep 13; 61(17):7448-7470. | ||||
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