General Information of DFM (ID: F23858)
Name	Oxytocin 10usp units/ml injectable
Company	Par Sterile Products
Active Pharmaceutical Ingredient (API)	Oxytocin		API Info click to show the detail info of this API
				Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E09EXY	DIG Info	Acetic acid	Acidulant ...
	E0FG5X	DIG Info	Anhydrous chlorobutanol	Antimicrobial preservative ...

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
G-protein coupled receptor (GPCR)
DBT Name: Free fatty acid receptor 2 (FFAR2)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Acetic acid
Biological Activity	IC50 = 120000 nM (tested by experiment)					[1]
Tested Species	Homo sapiens (Human)
UniProt ID	FFAR2_HUMAN
DBT Name: Free fatty acid receptor 3 (FFAR3)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Acetic acid
Biological Activity	EC50 = 12000 nM (tested by experiment)					[2]
Tested Species	Homo sapiens (Human)
UniProt ID	FFAR3_HUMAN

References
1	The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators. Bioorg Med Chem Lett. 2010 Jan 15; 20(2):493-8.
2	Microbiota-Host Transgenomic Metabolism, Bioactive Molecules from the Inside. J Med Chem. 2018 Jan 11; 61(1):47-61.

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