General Information of DIG (ID: E07RHX)
DIG Name
Ponceau 2R
Synonyms    Click to Show/Hide the Synonyms of This DIG
Acid Red 26; 3761-53-3; PONCEAU MX; Xylidine ponceau 2R; Xylidine Ponceau; Ponceau R; Ponceau xylidine; Ponceau 2R; Ponceau de Xylidine; C.I. Acid Red 26; Xylidine Red; CI F Food Red 5; Ponceau Red R; Ponceau G; Brilliant ponceau G; Lake ponceau; Ponceau fr; Ponceau gr; Ponceau nr; Ponceau rg; Acid Scarlet; Ponceau Red; Calcocid 2ril; C.I. Food Red 5; Ponceau J; Ponceaux MX; Kiton Ponceau R; Ponceau RR; Ponceau RS; Scarlet 2rl; Acetacid Red J; Acid Ponceau R; Java ponceau 2r; Lake Scarlet R; Ponceau BNA; Ponceau PXM; Scarlet RRA; Acidal Ponceau G; Edicol ponceau rs; Neklacid Red RR; Ponceau 2Re; Acid Scarlet 2B; Acid Scarlet 2R; Aizen Ponceau RH; Scarlet 2R; Acilan ponceau rrl; Pigment Ponceau R; Ponceau 2RL; Ponceau 2RX; Scarlet 2RB; Amacid scarlet 2r; Hispacid ponceau R; New Ponceau 4R; Paper Red HRR; Red For Lakes J; Kiton Ponceau 2R; Acid Ponceau 2RL; Acid Scarlet 2BN; Acid Scarlet 2RL; Acid Scarlet 2RN; Comacid scarlet 2r; Fenazo Scarlet 2R; Hexacol Ponceau MX; Kiton Scarlet 2RC; Red R; Hexacol Ponceau 2R; Hidacid Scarlet 2R; Lake Scarlet 2RBN; Acid Ponceau Special; Scarlet 2RL Bluish; Schultz no. 95; Calcocid Scarlet 2R; Xylidine Ponceau 3rs; Calcolake Scarlet 2R; Certicol Ponceau MXS; Naphthalene Scarlet R; Tertracid Ponceau 2R; Calcocid scarlet 2ril; C.I. 16150; Acid Leather Red KPR; Colacid Ponceau Special; Naphthazine Scarlet 2R; Acid Leather Red P2R; Ahcocid Fast Scarlet R; Edicol Supra Ponceau R; UNII-U3J3635T4U; Amacid Lake Scarlet 2R; Food Red No. 101; Acid Leather Scarlet IRW; D and C Red No. 5; D&C Red No. 5; Ponceau RR Type 8019; Naphthalene Lake Scarlet R; Acid Scarlet 2R For Lakes; Ponceau 2R Extra A Export; 1695 Red; Ponceau R (Biological stain); Ponceau 2R (Biological stain); Acid Scarlet 2R FOR Lakes Bluish; Ponceau Xylidine (Biological stain); C.I. Acid Red 26, Disodium Salt; C.I. 79; U3J3635T4U; 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-(2,4-xylylazo)-, disodium salt; MFCD00003897; Xylidine Ponceau 2R (C.l. 16150); Ponceaux 3R; D and C Red; Scarlet R (VAN); Tetracid Ponceau 2R; Disodium salt of 1-(2,4-xylylazo)-2-naphthol-3,6-disulfonic acid; Red No. 503; Cerven kysela 26 [Czech]; Red 101; Cerven kysela 26; 2,7-Naphthalenedisulfonic acid, 4-[2-(2,4-dimethylphenyl)diazenyl]-3-hydroxy-, sodium salt (1:2); CCRIS 164; Pas kwasowy 2 RL [Polish]; Pas kwasowy 2 RL; Cerven potravinarska 5 [Czech]; Cerven potravinarska 5; HSDB 2947; EINECS 223-178-3; NSC 10458; CI 16150; disodium 4-[(Z)-(2,4-dimethylphenyl)diazenyl]-3-hydroxy-2,7-naphthalenedisulfonate; disodium;4-[(E)-(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,7-disulfonate; Ponceau Xylidine;; 2,7-Naphthalenedisulfonic acid, 4-(2-(2,4-dimethylphenyl)diazenyl)-3-hydroxy-, sodium salt (1:2); Disodium 1-(2,4-dimethylphenylazo)-2-hydroxynaphthalene-3,6-disulphonate; Ponceau 2 R; 1-Xylylazo-2-naphthol-3,6-disulfonic acid, disodium salt; 1-Xylylazo-2-naphthol-3,6-disulphonic acid, disodium salt; 1-(2,4-Xylylazo)-2-naphthol-3,6-disulfonic acid, disodium salt; 1-(2,4-Xylylazo)-2-naphthol-3,6-disulphonic acid, disodium salt; Disodium salt of 1-(2,4-xylylazo)-2-naphthol-3,6-disulphonic acid; Disodium (2,4-dimethylphenylazo)-2-hydroxynaphthalene-3,6-disulfonate; Disodium (2,4-dimethylphenylazo)-2-hydroxynaphthalene-3,6-disulphonate; 3-Hydroxy-4-(2,4-xylylazo)-2,7-naphthalenedisulfonic acid, disodium salt; 2,7-Naphthalenedisulfonic acid, 4-((2,4-dimethylphenyl)azo)-3-hydroxy-, disodium salt; 4-((2,4-Dimethylphenyl)azo)-3-hydroxy-2,7-naphthalenedisulfonic acid, disodium salt; 4-((2,4-Dimethylphenyl)azo)-3-hydroxy-2,7-naphthalenedisulphonic acid, disodium salt; disodium 4-[2-(2,4-dimethylphenyl)diazen-1-yl]-3-hydroxynaphthalene-2,7-disulfonate; SCHEMBL6846278; CHEBI:82369; 6430AF; Ponceau Xylidine, analytical standard; 3-Hydroxy-4-(2,4-xylylazo)-2,7-naphthalenedisulphonic acid, disodium salt; AKOS000283082; AKOS015903398; AKOS024319210; NE18619; disodium 4-[(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,7-disulfonate; Ponceau Xylidine, Dye content >=60 %; C.I. Acid Red 26, disodium salt (8CI); P0590; EN300-60349; Acid Red 26 100 microg/mL in Acetonitrile:Water; sodium (E)-4-((2,4-dimethylphenyl)diazenyl)-3-hydroxynaphthalene-2,7-disulfonate
DIG Function
Colorant
PubChem CID
2724065
Formula
C18H14N2Na2O7S2
Canonical SMILES
CC1=CC(=C(C=C1)N=NC2=C3C=CC(=CC3=CC(=C2O)S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+]
InChI
1S/C18H16N2O7S2.2Na/c1-10-3-6-15(11(2)7-10)19-20-17-14-5-4-13(28(22,23)24)8-12(14)9-16(18(17)21)29(25,26)27;;/h3-9,21H,1-2H3,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2
InChIKey
YJVBLROMQZEFPA-UHFFFAOYSA-L
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2724065"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 480.4 Topological Polar Surface Area 176
XlogP N.A. Complexity 792
Heavy Atom Count 31 Rotatable Bond Count 2
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 9
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Potential-driven transporter (PDT)
            DBT Name: Solute carrier SLCO2B1 (OATPB) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio = 88.5 % (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 3.45 uM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
               Experiment (3) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 3.1 uM (tested by experiment) [2]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
References
1 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
2 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.