Details of the Drug Inactive Ingredient (DIG)
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
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G-protein coupled receptor (GPCR) | ||||||
DBT Name: Cannabinoid CB2 receptor (CNR2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 4.3 nM (estimated based on the structural similarity with CHEMBL2326300 ) | [1] | ||||
Structural Similarity | Tanimoto coefficient = 0.837037037 | |||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CNR2_HUMAN | |||||
Potential-driven transporter (PDT) | ||||||
DBT Name: Solute carrier SLCO2B1 (OATPB) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Inhibition ratio = 86.2 % (tested by experiment) | [2] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 0.8 uM (tested by experiment) | [2] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
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