Details of the Drug Inactive Ingredient (DIG)
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG | ||||||
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ICD Disease Classification 06 | Mental/behavioural/neurodevelopmental disorder | Click to Show/Hide | ||||
Risperidone
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API Info |
Schizophrenia [ICD-11: 6A20]
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[1] | |||
ICD Disease Classification 08 | Nervous system disease | Click to Show/Hide | ||||
Acetaminophen
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API Info |
Anaesthesia [ICD-11: 8E22]
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[2] | |||
Rizatriptan
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API Info |
Migraine [ICD-11: 8A80]
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[3] | |||
ICD Disease Classification 11 | Circulatory system disease | Click to Show/Hide | ||||
Nifedipine
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API Info |
Angina pectoris [ICD-11: BA40]
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[4] | |||
ICD Disease Classification 13 | Digestive system disease | Click to Show/Hide | ||||
Omeprazole
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API Info |
Gastro-oesophageal reflux disease [ICD-11: DA22]
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[5] | |||
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
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Transmembrane channel/porin (TC/P) | ||||||
DBT Name: Wasabi receptor (TRPA1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | EC50 = 30000 nM (tested by experiment) | [6] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | TRPA1_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | EC50 = 56000 nM (tested by experiment) | [7] | ||||
Tested Species | Mus musculus (Mouse) | |||||
UniProt ID | TRPA1_MOUSE | |||||
DBT Name: Transient receptor potential p8 (TRPM8) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | EC50 = 3000 nM (tested by experiment) | [8] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | TRPM8_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | EC50 = 75000 nM (tested by experiment) | [9] | ||||
Tested Species | Rattus norvegicus (Rat) | |||||
UniProt ID | TRPM8_RAT | |||||
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