Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0G5FT)
DIG Name
Sorbitan tristearate
Synonyms    Click to Show/Hide the Synonyms of This DIG
Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; [2-(4-hydroxy-3-octadecanoyloxyoxolan-2-yl)-2-octadecanoyloxyethyl] octadecanoate
DIG Function
Dispersing agent; Emulsifying agent; Solubilizing agent; Surfactant; Suspending agent; Vaccine adjuvant
PubChem CID
17800859
Formula
C60H114O8
Canonical SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(C1C(C(CO1)O)OC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC
InChI
1S/C60H114O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h54-55,59-61H,4-53H2,1-3H3
InChIKey
IJCWFDPJFXGQBN-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=17800859"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 963.5 Topological Polar Surface Area 108
XlogP 24.3 Complexity 1100
Heavy Atom Count 68 Rotatable Bond Count 56
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 8
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 01 Infectious/parasitic disease Click to Show/Hide
Raltegravir
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [1]
       ICD Disease Classification 02 Benign/in-situ/malignant neoplasm Click to Show/Hide
Tamoxifen
 API Info
Breast cancer [ICD-11: 2C60]
 [2]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Ranitidine
 API Info
Gastric ulcer [ICD-11: DA60]
 [3]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Cyclosporin A
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [4]
Tofacitinib
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [5]
       ICD Disease Classification 16 Genitourinary system disease Click to Show/Hide
Oxybutynin
 API Info
Overactive bladder [ICD-11: GC50]
 [6]
References
1 2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
2 FDA label for approved tamoxifen from the official website of the U.S. Food and Drug Administration.
3 FDA label for approved ranitidine from the official website of the U.S. Food and Drug Administration.
4 FDA label for approved cyclosporin A from the official website of the U.S. Food and Drug Administration.
5 FDA label for approved tofacitinib from the official website of the U.S. Food and Drug Administration.
6 FDA label for approved oxybutynin from the official website of the U.S. Food and Drug Administration.

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