Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0T3FM)
DIG Name
Sorbitan monooleate
Synonyms    Click to Show/Hide the Synonyms of This DIG
Sorbitan monooleate; Sorbitan, mono-(9Z)-9-octadecenoate; Arlacel 80; Span 80; SORBITAN OLEATE; UNII-06XEA2VD56; 06XEA2VD56; 1338-43-8; NCGC00164240-01; DSSTox_CID_7397; DSSTox_RID_78437; DSSTox_GSID_27397; 1,4-anhydro-6-O-[(9Z)-octadec-9-enoyl]-D-glucitol; Sorbitan oleate [INN]; CAS-1338-43-8; Sorbitani oleas; Glycomul O; Sorbitan O; Alkamuls SMO; Armotan MO; Dehymuls SMO; Lonzest SMO; NSC 406239; Oleate de sorbitan; Kosteran O 1; Oleato de sorbitano; Crill 4; Sorbester P 17; Disponil 100; Montan 80; Newcol 80; Nonion OP80R; Radiasurf 7155; Sorgen 40; Sorgen 40A; Montane 80 VGA; Rheodol AO 10; Atmer 05; Emasol O 10; Emasol O 10F; Kemmat S 80; Nikkol SO 10; Nikkol SO-15; Sorbon S 80; Emasol 410; Rheodol SP-O 10; Rikemal O 250; Sorbitan, mono-9-octadecenoate, (Z)-; Emsorb 2500; Ionet S-80; Span-80; S 271 (surfactant); Nissan Nonion OP 80R; Anhydrosorbitol monooleate; Mannide monooleate, liquid; Dianhydromannitol monooleate; SCHEMBL4504; Span(R) 80, for GC; Monodehydrosorbitol monooleate; Sorbitan monooleic acid ester; CCRIS 710; Sorbitani oleas [INN-Latin]; Mannide monooleate, from plant; ML 55F; MO 33F; S-MAX 80; Sorbitan monooleate [USAN:NF]; CHEMBL1894187; DTXSID6027397; HSDB 5822; Oleate de sorbitan [INN-French]; Span(R) 80, nonionic surfactant; 1,4-Anhydro-D-glucitol 6-oleate; Oleato de sorbitano [INN-Spanish]; ZINC8214458; EINECS 215-665-4; Tox21_113539; Tox21_300389; Sorbitan monooleate, SAJ first grade; AKOS024431316; NCGC00164240-02; NCGC00254386-01; S 80; Sorbitan esters, mono(Z)-9-octadecenoate; G 946; O 250; S 270; S0060; 1,4-Anhydro-D-glucitol, 6-(9-octadecenoate); D-Glucitol, 1,4-anhydro-, 6-(9-octadecenoate); J-006443; Q2303156; Span(R) 80, viscosity 1000-2000 mPa.s (20 C); UNII-MDL271E3GR component NWGKJDSIEKMTRX-AAZCQSIUSA-N; [(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] (Z)-octadec-9-enoate; Sorbitan monooleate. (Compound usually contains also associated fatty acids.)
DIG Function
Dispersing agent; Emulsifying agent; Solubilizing agent; Surfactant; Suspending agent; Vaccine adjuvant
PubChem CID
9920342
Formula
C24H44O6
Canonical SMILES
CCCCCCCC/C=C\\CCCCCCCC(=O)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O
InChI
1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1
InChIKey
NWGKJDSIEKMTRX-AAZCQSIUSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=9920342"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 428.6 Topological Polar Surface Area 96.2
XlogP 6 Complexity 453
Heavy Atom Count 30 Rotatable Bond Count 19
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 6
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 12 Respiratory system disease Click to Show/Hide
Clarithromycin
 API Info
Pneumocystis pneumonia [ICD-11: CA40]
 [1]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Bisacodyl
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [2]
       ICD Disease Classification 14 Skin disease Click to Show/Hide
Isotretinoin
 API Info
Acne vulgaris [ICD-11: ED80]
 [3]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Cyclosporin A
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [4]
       ICD Disease Classification 16 Genitourinary system disease Click to Show/Hide
Ibuprofen
 API Info
Dysmenorrhea [ICD-11: GA34]
 [5]
Erythromycin
 API Info
Pelvic inflammatory disease [ICD-11: GA05]
 [6]
References
1 FDA label for approved clarithromycin from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved bisacodyl from the official website of the U.S. Food and Drug Administration.
3 FDA label for approved isotretinoin from the official website of the U.S. Food and Drug Administration.
4 FDA label for approved cyclosporin A from the official website of the U.S. Food and Drug Administration.
5 FDA label for approved ibuprofen from the official website of the U.S. Food and Drug Administration.
6 FDA label for approved erythromycin from the official website of the U.S. Food and Drug Administration.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.