Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00198) | |||||
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Name |
Digoxin
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Synonyms |
Click to Show/Hide the Synonyms of This API
digoxin; 20830-75-5; Lanoxin; 12beta-Hydroxydigitoxin; Dilanacin; Lanoxicaps; Digacin; Digosin; Digoxin Pediatric; Davoxin; Rougoxin; CHEBI:4551; MLS000069819; MFCD00003674; Cardiogoxin; Lanacordin; Cordioxil; Dynamos; Eudigox; Lanacrist; Lenoxin; Mapluxin; SMR000059217; Vanoxin; Neo-Lanicor; Digoxin Nativelle; Lanoxin PG; SK-Digoxin; UNII-73K4184T59; Homolle's digitalin; 20830-75-5 (free); C41H64O14; NSC 95100; Digoxin, 95%; NCGC00090797-03; 73K4184T59; DSSTox_CID_2934; Digoxin, analytical standard; DSSTox_RID_76794; Coragoxine; DSSTox_GSID_22934; Lenoxicaps; Neodioxanin; Cardigox; Cardioxin; Digomal; Fargoxin; Lanikor; Lanorale; Natigoxin; Purgoxin; Dixina; Grexin; Digitek; Digoxine; Chloroformic digitalin; Lanoxicaps (TN); [3H]digoxin; SMR000653537; Hemigoxine Nativelle; Lanoxin (TN); [3H]-digoxin; Acygoxin; Digoksyna; Digonix; Digossina; Digoxina; Digoxinum; Dimecip; Lifusin; Saroxin; Digoxin-Sandoz; Digoxina-Sandoz; Digoxin-Zori; NSC-95100; Digoxine Navtivelle; Novodigal [inj.]; Prestwick_170; Digoksyna [Polish]; Digossina [DCIT]; CAS-20830-75-5; 12A-Hydroxydigitoxin; 12??-Hydroxydigitoxin; LANOXIN PEDIATRIC; Digoxinum [INN-Latin]; 12bet.-Hydroxydigitoxin; Digoxigenin-tridigitoxosid; Digoxina [INN-Spanish]; Opera_ID_1134; Prestwick0_000437; Prestwick1_000437; Prestwick2_000437; Prestwick3_000437; Digoxin (JP17/USP); Epitope ID:122964; CHEMBL1751; BIDD:PXR0148; SCHEMBL20506; BSPBio_000454; MLS001055371; MLS001076495; SPBio_002393; BPBio1_000500; GTPL4725; GTPL4726; HSDB 214; Digoxin [USP:INN:BAN:JAN]; Digoxin 1.0 mg/ml in Methanol; DTXSID5022934; BDBM46355; cid_2724385; REGID_for_CID_2724385; HMS1569G16; HMS2096G16; HMS2232G20; HMS3713G16; Digoxigenin-tridigitoxosid [German]; HY-B1049; EINECS 244-068-1; Tox21_111025; Tox21_201678; Tox21_303050; AKOS015895113; AKOS024283494; ZINC242548690; CCG-220437; CS-4571; DB00390; MCULE-8165628529; BRN 0077011; NCGC00090797-01; NCGC00090797-02; NCGC00090797-04; NCGC00090797-05; NCGC00090797-06; NCGC00090797-07; NCGC00090797-09; NCGC00090797-12; NCGC00090797-15; NCGC00257022-01; NCGC00259227-01; AS-13281; ST069334; C06956; D00298; J10027; 5-18-04-00381 (Beilstein Handbook Reference); 830D755; A814956; Q422222; SR-01000721866; Digoxin, certified reference material, TraceCERT(R); J-013666; SR-01000721866-3; SR-01000721866-4; BRD-K23478508-001-03-7; Digoxin, European Pharmacopoeia (EP) Reference Standard; 0B9662A7-264E-4ACD-94B2-9E1138C0CA5A; Digoxin, United States Pharmacopeia (USP) Reference Standard; Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material; 3beta,12beta,14-Trihydroxy-5beta,14beta-card-20(22)-enolid-3-tridigitoxosid; Digoxin for peak identification, European Pharmacopoeia (EP) Reference Standard
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Clinical Status |
Approved
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Disease Indication | Cardiac arrhythmia | ICD-11: BC65 | [1] | ||
PubChem CID | |||||
Formula |
C41H64O14
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Canonical SMILES |
C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)O
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InChI |
1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
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InChIKey |
LTMHDMANZUZIPE-PUGKRICDSA-N
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2724385"></iframe>
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3D MOL is unavailable | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 780.9 | Topological Polar Surface Area | 203 | |
XlogP | 1.3 | Complexity | 1450 | ||
Heavy Atom Count | 55 | Rotatable Bond Count | 7 | ||
Hydrogen Bond Donor Count | 6 | Hydrogen Bond Acceptor Count | 14 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Digoxin 0.125 mg tablet | Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Carilion Materials Management; Jerome Stevens Pharmaceuticals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Lannett Company; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; PD-Rx Pharmaceuticals; Proficient Rx; St Marys Medical Park Pharmacy; TYA Pharmaceuticals; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Starch, corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Dept Health Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Starch, corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care; State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Bryant Ranch Prepack; Cardinal Health; Golden State Medical Supply; NuCare Pharmaceuticals; West-Ward Pharmaceticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Colloidal silicon dioxide; Starch, corn; Starch, pregelatinized corn
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Dosage Form | Oral Tablet | |||||
Company | McKesson | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Colloidal silicon dioxide; Starch, corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Major Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Avera McKennan Hospital; Cardinal Health; Concordia Pharmaceuticals; Covis Pharmaceuticals; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Par Pharmaceutical; RemedyRepack; State of Florida DOH Central Pharmacy; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Hypromellose 2208 (15000 mpa.s)
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Dosage Form | Oral Tablet | |||||
Company | NorthStar Rx; Sun Pharmaceutical Industries; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 5; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Hypromellose 2208 (15000 mpa.s)
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Dosage Form | Oral Tablet | |||||
Company | Rebel Distributors; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 5; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Cardinal Health; Impax Generics | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 5; Magnesium stearate; Microcrystalline cellulose; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Silicon dioxide; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Digoxin 0.25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 12 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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Dosage Form | Oral Tablet | |||||
Company | Aidarex Pharmaceuticals; Jerome Stevens Pharmaceuticals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Lannett Company; NCS HealthCare of KY, Inc dba Vangard Labs; PD-Rx Pharmaceuticals; St Marys Medical Park Pharmacy; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Lactose monohydrate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Hypromellose 2208 (15000 mpa.s)
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Dosage Form | Oral Tablet | |||||
Company | NorthStar Rx; Sun Pharmaceutical Industries; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Silicon dioxide; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Cardinal Health; Golden State Medical Supply; NCS HealthCare of KY, Inc dba Vangard Labs; West-Ward Pharmaceticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Silicon dioxide; Starch, corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Physicians Total Care; State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Colloidal silicon dioxide; Starch, corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Major Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Impax Generics; State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Microcrystalline cellulose; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee; GlaxoSmithKline; PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Avera McKennan Hospital; Cardinal Health; Concordia Pharmaceuticals; Covis Pharmaceuticals; NuCare Pharmaceuticals; Par Pharmaceutical; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Digoxin 125 mcg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Colloidal silicon dioxide; Starch, corn; Starch, pregelatinized corn
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Dosage Form | Oral Tablet | |||||
Company | Cardinal Health; UDL Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Digoxin 0.0625 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Concordia Pharmaceuticals; Covis Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Digoxin 0.1875 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c green no. 5; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Concordia Pharmaceuticals; Covis Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C green no. 5 | DIG Info | Solute carrier SLCO2B1 (Ki = 1.54 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Digoxin 250 mcg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Colloidal silicon dioxide; Starch, corn; Starch, pregelatinized corn
|
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Dosage Form | Oral Tablet | |||||
Company | UDL Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Magnesium stearate; Starch, corn; Starch, potato
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Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [3] | |||
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