Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E06VNY)
DIG Name
Stearic acid
Synonyms    Click to Show/Hide the Synonyms of This DIG
stearic acid; Octadecanoic acid; 57-11-4; Stearophanic acid; n-Octadecanoic acid; Cetylacetic acid; Pearl stearic; Stearex Beads; Octadecansaeure; Stearinsaeure; Vanicol; 1-Heptadecanecarboxylic acid; Century 1240; Industrene R; Glycon DP; Glycon TP; Humko Industrene R; Dar-chem 14; Formula 300; Hydrofol 1895; Hystrene 9718; Hydrofol Acid 150; Glycon S-80; Glycon S-90; Hydrofol acid 1655; Hydrofol acid 1855; Tegostearic 254; Tegostearic 255; Tegostearic 272; Hystrene 80; octadecoic acid; Industrene 5016; Hystrene S-97; Hystrene T-70; Emersol 120; Emersol 132; Hystrene 4516; Hystrene 5016; Hystrene 7018; Groco 54; Groco 55; Groco 55L; Groco 58; Groco 59; Glycon S-70; Industrene 8718; Industrene 9018; Kam 1000; Emersol 150; Steric acid; Neo-Fat 18-53; Neo-Fat 18-54; Neo-Fat 18-59; Neo-Fat 18; Acidum stearinicul; Caswell No. 801D; HY-Phi 1199; HY-Phi 1205; HY-Phi 1303; HY-Phi 1401; Neo-Fat 18-S; C18:0; Kam 2000; Kam 3000; Oktadekansaeure; Neo-Fat 18-55; Neo-Fat 18-61; acide stearique; FEMA No. 3035; PD 185; acide octadecanoique; NAA 173; Hydrofol Acid 150 (VAN); CCRIS 2305; Prifac 2918; HSDB 2000; Vis-Plus; Barolub FTA; UNII-4ELV7Z65AP; MFCD00002752; NSC 25956; Prodhygine; EPA Pesticide Chemical Code 079082; Stearic Acid Cherry; Edenor C18; Stearic acid (TN); CH3-[CH2]16-COOH; Flexichem B; Loxiol G 20; Century 1210; Century 1220; Century 1230; Emersol 6349; AI3-00909; Lunac S 20; Lunac S 40; WO 2 (fatty acid); Hydrofol Acid 1895; Bonderlube 235; 4ELV7Z65AP; Adeka Fatty Acid SA 910; CHEMBL46403; CHEBI:28842; NSC25956; Stearic acid, 97%; NCGC00091596-02; DSSTox_CID_1642; DSSTox_RID_76256; 124-26-5 (amide) 57-11-4 (free base); DSSTox_GSID_21642; Stearic acid, pure; Lunac; Stearic Acid (Powder/Beads/Flakes); Fatty acids, C16-20; CAS-57-11-4; Isostearic acid EX; Haimaric MKH(R); Prisorine 3501; Prisorine 3502; Prisorine 3508; Emersol 153NF; Emersol 871; Emersol 875; Emery 875D; Emery 871; Unimac 5680; C-Lube 10; EINECS 200-313-4; Stearic acid [JAN:NF]; BRN 0608585; Stearophanate; Promulsin; Stearex; Tsubaki; n-Octadecanoate; Bassinic acid; Lactaric acid; Talgic acid; 1hmr; 1hmt; 4fnn; Kiri stearic acid; Edenor FHTI; Lunac YA; n-Octadecylic acid; Stearic acid, CP; EINECS 250-178-0; EINECS 273-087-8; F 3 (lubricant); Industrene 4518; Nonsoul SK 1; Pristerene 4900; Pristerene 4904; Pristerene 4963; Pristerene 9429; Pristerene 9559; Hystrene S 97; Hystrene T 70; Edenor ST 1; Sunfat 18S; Emersol 153; Selosol 920; Industrene 5016K; Stearic Acid 110; Stearic Acid 120; Stearic Acid 420; Hystrene 9718NF; Kortacid 1895; Radiacid 0427; Edenor ST 20; Lunac 30; Serfax MT 90; Stearic acid_ravikumar; Unister NAA 180; Century 1224; Edenor HT-JG 60; Lunac S 90KC; Stearic acid (8CI); Stearic acid, puriss.; Hystrene 7018 FG; Hystrene 9718NFFG; Lunac S 30; Lunac S 50; Lunac S 90; Lunac S 98; 3v2p; 875D; 1-Heptadecanecarboxylate; Industrene 7018 FG; Stearic Acid NF Powder; AFCO-Chem B 65; Stearic Acid - 65%; Stearic Acid - 70%; Stearic Acid 153 NF; Heptadecanecarboxylic acid; Stearic Acid & Glycerin; Edenor C 18/98; S 300 (fatty acid); Octadecanoic acid (9CI); Stearic acid, >=98%; ACMC-1AR8K; SCHEMBL659; Hystrene 9718 NF FG; SA 400 (fatty acid); bmse000485; Stearic Acid, High Purity; Stearic acid-[13C18]; Stearic acid-2-[13C]; EC 200-313-4; Emery 400 (Salt/Mix); Octadecanoic-4,4-d2 acid; Stearic acid (JP15/NF); Stearic acid (JP17/NF); Stearic Acid Triple-Pressed; Triple Pressed Stearic Acid; Emersol 110 (Salt/Mix); Stearic Acid - High Purity; 4-02-00-01206 (Beilstein Handbook Reference); 68937-76-8; WLN: QV17; Agar Agar Type K-100 NF; Stearic Acid - Triple Pressed; 17FA; GTPL3377; WO 2; Stearic Acid (Fragrance Grade); Stearic Acid High Purity 90%; Stearic acid-1,2-[13C2]; DTXSID8021642; Nonsoul SN 1 (*Sodium salt*); OCTADECANOIC-12-D1 ACID; S 30C S 30C (fatty acid); SNA-2000 (*Sodium salt*); Stearic acid, analytical standard; VLZ 200; CCCCCCCCCCCCCCCCCC([O])=O; Octadecanoic-2,2-d2acid (9CI); Stearic Acid High Purity 90% V; Stearic Acid Flake 132 NF Flake; Stearic acid, reagent grade, 95%; HY-B2219; Stearic Acid 400 (Rubber Grade); ZINC4978673; Tox21_111154; Tox21_201887; Tox21_300562; ANW-13575; BBL012224; BDBM50240485; LMFA01010018; NSC-25956; s5733; SA 200; SBB060276; Stearic acid, >=95%, FCC, FG; STL163565; AKOS005716958; Tox21_111154_1; CCG-267314; DB03193; FA 1655; MCULE-5127577640; NE10227; NSC 261168; T16-55F; NCGC00091596-01; NCGC00091596-03; NCGC00091596-04; NCGC00091596-05; NCGC00254456-01; NCGC00259436-01; E570; I727; ST023799; VS-03242; OCTADECANOIC-9,9,10,10-D4 ACID; Stearic acid, puriss., >=98.5% (GC); Stearic acid, SAJ first grade, >=90.0%; BB 0268543; CS-0021598; FT-0674650; FT-0689088; G 270; S 300; S0163; Stearic-17,17,18,18,18-[d5] acid; Stearic acid, SAJ special grade, >=95.0%; Stearic acid, Vetec(TM) reagent grade, 94%; 400JB9103-88; A 1760; C01530; D00119; EC 250-178-0; Stearic acid 50, tested according to Ph.Eur.; Vegetable Stearic Acid 7036 FG, Kosher, NF; Q209685; SR-01000944717; Melting Point Standard 69-71C, analytical standard; SR-01000944717-1; Stearic acid, Grade I, >=98.5% (capillary GC); Stearic acid, SAJ first grade, >=90.0%, powder; F0001-1489; Stearic acid, certified reference material, TraceCERT(R); Z955123678; UNII-13FB83DEYU component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-44NH37HHP9 component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-5U9XZ261ER component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-7N137Q0QYJ component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-96GS7P39SN component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-B6G0Y5Z616 component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-D1CZ545P7Z component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-HBA528N3PW component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-J505W0PXX8 component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-MO7HV04S9Y component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-ODL221H4AM component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-Q8Y7S3B85M component QIQXTHQIDYTFRH-UHFFFAOYSA-N; UNII-X33R8U0062 component QIQXTHQIDYTFRH-UHFFFAOYSA-N; CD7993EA-AD14-452A-A907-33376CC98790; Stearic acid, European Pharmacopoeia (EP) Reference Standard; UNII-79P21R4317 component QIQXTHQIDYTFRH-UHFFFAOYSA-N; Stearic acid, United States Pharmacopeia (USP) Reference Standard; Stearic Acid, Pharmaceutical Secondary Standard; Certified Reference Material; 130048-57-6; 211443-83-3; 62163-41-1; 62690-13-5
DIG Function
Emulsifying agent; Solubilizing agent; Viscosity-controlling agent; lubricant
PubChem CID
5281
Formula
C18H36O2
Canonical SMILES
CCCCCCCCCCCCCCCCCC(=O)O
InChI
1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20)
InChIKey
QIQXTHQIDYTFRH-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5281"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 284.5 Topological Polar Surface Area 37.3
XlogP 7.4 Complexity 202
Heavy Atom Count 20 Rotatable Bond Count 16
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 2
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 01 Infectious/parasitic disease Click to Show/Hide
Minocycline
 API Info
Streptococcus bacterial infection [ICD-11: 1C41]
 [1]
Metronidazole
 API Info
Amebiasis [ICD-11: 1A36]
 [2]
Oseltamivir
 API Info
Influenza virus infection [ICD-11: 1E30]
 [3]
Tetracycline
 API Info
Spotted fever [ICD-11: 1C31]
 [4]
Famciclovir
 API Info
Genital herpes [ICD-11: 1A94]
 [5]
Ethambutol
 API Info
Pulmonary tuberculosis [ICD-11: 1B10]
 [6]
Isoniazid
 API Info
Pulmonary tuberculosis [ICD-11: 1B10]
 [7]
Ciprofloxacin
 API Info
Endocarditis [ICD-11: 1B12]
 [8]
Mebendazole
 API Info
Ascariasis [ICD-11: 1F62]
 [9]
Pyrazinamide
 API Info
Pulmonary tuberculosis [ICD-11: 1B10]
 [10]
Valganciclovir
 API Info
Cytomegalovirus infection [ICD-11: 1D82]
 [11]
Sulfadiazine
 API Info
Toxoplasmosis [ICD-11: 1F57]
 [12]
       ICD Disease Classification 02 Benign/in-situ/malignant neoplasm Click to Show/Hide
Temozolomide
 API Info
Brain cancer [ICD-11: 2A00]
 [13]
Nicotinic acid
 API Info
Lung cancer [ICD-11: 2C25]
 [14]
Mercaptopurine
 API Info
Acute lymphoblastic leukemia [ICD-11: 2B33]
 [15]
Nystatin
 API Info
Acute lymphoblastic leukemia [ICD-11: 2B33]
 [16]
Chlorambucil
 API Info
Chronic lymphocytic leukaemia [ICD-11: 2A82]
 [17]
Thioguanine
 API Info
Acute myeloid leukemia [ICD-11: 2A60]
 [18]
Cabozantinib
 API Info
Thyroid cancer [ICD-11: 2D10]
 [19]
       ICD Disease Classification 04 Immune system disease Click to Show/Hide
Methylprednisolone
 API Info
Systemic lupus erythematosus [ICD-11: 4A40]
 [20]
       ICD Disease Classification 05 Endocrine/nutritional/metabolic disease Click to Show/Hide
Phentermine
 API Info
Obesity [ICD-11: 5B81]
 [21]
Potassium chloride
 API Info
Hypokalemia [ICD-11: 5C77]
 [22]
Glipizide
 API Info
Diabetes mellitus [ICD-11: 5A10]
 [23]
Metformin
 API Info
Diabetes mellitus [ICD-11: 5A10]
 [24]
Phendimetrazine
 API Info
Obesity [ICD-11: 5B81]
 [25]
Fenofibric acid
 API Info
Dyslipidaemia [ICD-11: 5C81]
 [26]
Folic acid
 API Info
Vitamin deficiency [ICD-11: 5B55]
 [27]
Liothyronine
 API Info
Hypothyroidism [ICD-11: 5A00]
 [28]
Sodium bicarbonate
 API Info
Metabolic acidosis [ICD-11: 5C73]
 [29]
Pyridoxine
 API Info
Vitamin deficiency [ICD-11: 5B55]
 [30]
Trientine
 API Info
Hyperphosphatemia [ICD-11: 5C64]
 [31]
       ICD Disease Classification 06 Mental/behavioural/neurodevelopmental disorder Click to Show/Hide
Risperidone
 API Info
Schizophrenia [ICD-11: 6A20]
 [32]
Bupropion
 API Info
Nicotine dependence [ICD-11: 6C4A]
 [33]
Lamotrigine
 API Info
Bipolar disorder [ICD-11: 6A60]
 [34]
Fluoxetine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [35]
Hydroxyzine
 API Info
Anxiety disorder [ICD-11: 6B00]
 [36]
Methylphenidate
 API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
 [37]
Guanfacine
 API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
 [38]
Lithium carbonate
 API Info
Bipolar disorder [ICD-11: 6A60]
 [39]
Imipramine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [40]
Prochlorperazine
 API Info
Schizophrenia [ICD-11: 6A20]
 [41]
Desipramine
 API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
 [42]
Trazodone
 API Info
Major depressive disorder [ICD-11: 6A70]
 [43]
Paliperidone
 API Info
Bipolar disorder [ICD-11: 6A60]
 [44]
Carisoprodol
 API Info
Major depressive disorder [ICD-11: 6A70]
 [45]
Amphetamine
 API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
 [46]
Meprobamate
 API Info
Anxiety disorder [ICD-11: 6B00]
 [47]
Disulfiram
 API Info
Alcohol dependence [ICD-11: 6C40]
 [48]
Amoxapine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [49]
Methamphetamine
 API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
 [50]
       ICD Disease Classification 07 Sleep-wake disorder Click to Show/Hide
Dextroamphetamine
 API Info
Narcolepsy [ICD-11: 7A20]
 [51]
Zolpidem
 API Info
Insomnia [ICD-11: 7A00]
 [52]
Zaleplon
 API Info
Insomnia [ICD-11: 7A00]
 [53]
Estazolam
 API Info
Insomnia [ICD-11: 7A00]
 [54]
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Acetaminophen
 API Info
Anaesthesia [ICD-11: 8E22]
 [55]
Morphine
 API Info
Anaesthesia [ICD-11: 8E22]
 [56]
Oxycodone
 API Info
Anaesthesia [ICD-11: 8E22]
 [57]
Valproic acid
 API Info
Epilepsy [ICD-11: 8A60]
 [58]
Propranolol
 API Info
Migraine [ICD-11: 8A80]
 [59]
Levetiracetam
 API Info
Focal seizure [ICD-11: 8A68]
 [60]
Carbamazepine
 API Info
Epilepsy [ICD-11: 8A60]
 [61]
Tizanidine
 API Info
Tic disorder [ICD-11: 8A05]
 [62]
Hydromorphone
 API Info
Anaesthesia [ICD-11: 8E22]
 [63]
Zonisamide
 API Info
Epilepsy [ICD-11: 8A60]
 [64]
Rivastigmine
 API Info
Alzheimer disease [ICD-11: 8A20]
 [65]
Meperidine
 API Info
Anaesthesia [ICD-11: 8E22]
 [66]
Tiagabine
 API Info
Epilepsy [ICD-11: 8A60]
 [67]
Primidone
 API Info
Epilepsy [ICD-11: 8A60]
 [68]
Carprofen
 API Info
Anaesthesia [ICD-11: 8E22]
 [69]
Chlorthalidone
 API Info
Huntington disease [ICD-11: 8A01]
 [70]
Codeine
 API Info
Anaesthesia [ICD-11: 8E22]
 [71]
Rasagiline
 API Info
Parkinsonism [ICD-11: 8A00]
 [72]
Methylergonovine
 API Info
Migraine [ICD-11: 8A80]
 [73]
Phenobarbital
 API Info
Epilepsy [ICD-11: 8A60]
 [74]
Pyridostigmine
 API Info
Myasthenia gravis [ICD-11: 8C60]
 [75]
Selegiline
 API Info
Parkinsonism [ICD-11: 8A00]
 [76]
Methadone
 API Info
Anaesthesia [ICD-11: 8E22]
 [77]
Ticlopidine
 API Info
Cerebral stroke [ICD-11: 8B11]
 [78]
Ethotoin
 API Info
Focal seizure [ICD-11: 8A68]
 [79]
Dihydroergotamine
 API Info
Migraine [ICD-11: 8A80]
 [80]
Levorphanol
 API Info
Cerebral stroke [ICD-11: 8B11]
 [81]
       ICD Disease Classification 09 Visual system disease Click to Show/Hide
Pilocarpine
 API Info
Glaucoma [ICD-11: 9C61]
 [82]
       ICD Disease Classification 10 Ear/mastoid process disease Click to Show/Hide
Diphenhydramine
 API Info
Meniere disease [ICD-11: AB31]
 [83]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Diltiazem
 API Info
Essential hypertension [ICD-11: BA00]
 [84]
Aspirin
 API Info
Myocardial infarction [ICD-11: BA41]
 [85]
Hydralazine
 API Info
Essential hypertension [ICD-11: BA00]
 [86]
Losartan
 API Info
Essential hypertension [ICD-11: BA00]
 [87]
Enalapril
 API Info
Essential hypertension [ICD-11: BA00]
 [88]
Caffeine
 API Info
Orthostatic hypotension [ICD-11: BA21]
 [89]
Captopril
 API Info
Essential hypertension [ICD-11: BA00]
 [90]
Amlodipine
 API Info
Angina pectoris [ICD-11: BA40]
 [91]
Propafenone
 API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
 [92]
Sotalol
 API Info
Atrial fibrillation [ICD-11: BC81]
 [93]
Benazepril
 API Info
Essential hypertension [ICD-11: BA00]
 [94]
Spironolactone
 API Info
Congestive heart failure [ICD-11: BD10]
 [95]
Digoxin
 API Info
Cardiac arrhythmia [ICD-11: BC65]
 [96]
Amiodarone
 API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
 [97]
Furosemide
 API Info
Congestive heart failure [ICD-11: BD10]
 [98]
Isosorbide dinitrate
 API Info
Angina pectoris [ICD-11: BA40]
 [99]
Dipyridamole
 API Info
Atherosclerosis [ICD-11: BA80]
 [100]
Acebutolol
 API Info
Essential hypertension [ICD-11: BA00]
 [101]
Olmesartan
 API Info
Essential hypertension [ICD-11: BA00]
 [102]
Prasugrel
 API Info
Myocardial infarction [ICD-11: BA41]
 [103]
Flecainide
 API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
 [92]
Betaxolol
 API Info
Essential hypertension [ICD-11: BA00]
 [104]
       ICD Disease Classification 12 Respiratory system disease Click to Show/Hide
Guaifenesin
 API Info
Asthma [ICD-11: CA23]
 [105]
Clarithromycin
 API Info
Pneumocystis pneumonia [ICD-11: CA40]
 [106]
Chlorpheniramine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [107]
Fexofenadine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [108]
Promethazine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [109]
Loratadine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [110]
Budesonide
 API Info
Allergic rhinitis [ICD-11: CA08]
 [111]
Clemastine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [112]
Salbutamol
 API Info
Chronic obstructive pulmonary disease [ICD-11: CA22]
 [113]
Dexbrompheniramine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [114]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Doxycycline
 API Info
Periodontal disease [ICD-11: DA0C]
 [115]
Bisacodyl
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [116]
Pantoprazole
 API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
 [117]
Meclizine
 API Info
Functional nausea/vomiting [ICD-11: DD90]
 [118]
Simethicone
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [119]
Bismuth subsalicylate
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [120]
Dicyclomine
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [121]
Metoclopramide
 API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
 [122]
Rabeprazole
 API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
 [123]
Mesalamine
 API Info
Inflammatory bowel disease [ICD-11: DD72]
 [124]
Dimenhydrinate
 API Info
Functional nausea/vomiting [ICD-11: DD90]
 [125]
Mycophenolic acid
 API Info
Crohn disease [ICD-11: DD70]
 [126]
       ICD Disease Classification 14 Skin disease Click to Show/Hide
Hydrochlorothiazide
 API Info
Luid retention [ICD-11: EF02]
 [127]
Pseudoephedrine
 API Info
Erythema multiforme [ICD-11: EB12]
 [128]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Naproxen
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [129]
Indomethacin
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [130]
Diclofenac
 API Info
Knee osteoarthritis [ICD-11: FA01]
 [131]
Etodolac
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [132]
Phenylephrine
 API Info
Juvenile rheumatoid arthritis [ICD-11: FA24]
 [133]
Methocarbamol
 API Info
Paget's disease [ICD-11: FB85]
 [134]
Prednisone
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [135]
Allopurinol
 API Info
Uncontrolled gout [ICD-11: FA25]
 [136]
Dexamethasone
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [137]
Metaxalone
 API Info
Myalgia [ICD-11: FB56]
 [138]
Sulindac
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [139]
Azathioprine
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [140]
Ibandronic acid
 API Info
Osteoporosis [ICD-11: FB83]
 [141]
Oxaprozin
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [142]
Sulfasalazine
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [143]
       ICD Disease Classification 16 Genitourinary system disease Click to Show/Hide
Ibuprofen
 API Info
Dysmenorrhea [ICD-11: GA34]
 [144]
Terazosin
 API Info
Prostatic hyperplasia [ICD-11: GA90]
 [145]
Erythromycin
 API Info
Pelvic inflammatory disease [ICD-11: GA05]
 [146]
Tolterodine
 API Info
Overactive bladder [ICD-11: GC50]
 [147]
Sevelamer
 API Info
Chronic kidney disease [ICD-11: GB61]
 [148]
Danazol
 API Info
Endometriosis [ICD-11: GA10]
 [149]
Aminocaproic acid
 API Info
Menorrhagia [ICD-11: GA20]
 [150]
Trospium
 API Info
Overactive bladder [ICD-11: GC50]
 [151]
Potassium citrate
 API Info
Urinary calculus [ICD-11: GB70]
 [152]
Tranexamic acid
 API Info
Excessive bleeding [ICD-11: GA30]
 [153]
Trimethoprim
 API Info
Infectious cystitis [ICD-11: GC00]
 [154]
       ICD Disease Classification 20 Developmental anomaly Click to Show/Hide
Estradiol
 API Info
Turner syndrome [ICD-11: LD50]
 [155]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      G-protein coupled receptor (GPCR)
            DBT Name: Adenosine receptor A3 (AA3R) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 10 uM (tested by experiment) [156]
                    Tested Species Homo sapiens (Human)
                    UniProt ID AA3R_HUMAN
      Oxidoreductase (ORase)
            DBT Name: Prostaglandin G/H synthase 1 (COX-1) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 > 500000 nM (tested by experiment) [157]
                    Tested Species Bos taurus (Bovine)
                    UniProt ID PGH1_BOVIN
            DBT Name: Prostaglandin G/H synthase 2 (COX-2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 > 500000 nM (tested by experiment) [157]
                    Tested Species Ovis aries (Sheep)
                    UniProt ID PGH2_SHEEP
      Hydrolase (HDase)
            DBT Name: Phosphodiesterase 3A (PDE3A) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 3.1 uM (tested by experiment) [156]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PDE3A_HUMAN
            DBT Name: Phosphodiesterase 4D (PDE4D) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 6.7 uM (tested by experiment) [156]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PDE4D_HUMAN
      Nuclear receptor (NR)
            DBT Name: Estrogen receptor alpha (ESR1) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 16 uM (tested by experiment) [156]
                    Tested Species Homo sapiens (Human)
                    UniProt ID ESR1_HUMAN
            DBT Name: PPAR-alpha (PPARA) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 1100 nM (tested by experiment) [158]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PPARA_HUMAN
            DBT Name: PPAR-delta (PPARD) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 6000 nM (tested by experiment) [158]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PPARD_HUMAN
            DBT Name: PPAR-gamma (PPARG) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 30000 nM (tested by experiment) [158]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PPARG_HUMAN
      Cell line (CELL)
            DBT Name: Colon cancer COLO 205 cells (COLO 205) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 > 200000 nM (tested by experiment) [159]
                    Tested Species Homo sapiens (Human)
                    Cellosaurus ID CVCL_0218
            DBT Name: Colon cancer HT-29 cells (HT-29) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 > 200000 nM (tested by experiment) [159]
                    Tested Species Homo sapiens (Human)
                    Cellosaurus ID CVCL_0320
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63 FDA label for approved hydromorphone from the official website of the U.S. Food and Drug Administration.
64 FDA label for approved zonisamide from the official website of the U.S. Food and Drug Administration.
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119 FDA label for approved simethicone from the official website of the U.S. Food and Drug Administration.
120 Bismuth Subsalicylate.
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123 FDA label for approved rabeprazole from the official website of the U.S. Food and Drug Administration.
124 FDA label for approved mesalamine from the official website of the U.S. Food and Drug Administration.
125 FDA label for approved dimenhydrinate from the official website of the U.S. Food and Drug Administration.
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130 FDA label for approved indomethacin from the official website of the U.S. Food and Drug Administration.
131 FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
132 FDA label for approved etodolac from the official website of the U.S. Food and Drug Administration.
133 FDA label for approved phenylephrine from the official website of the U.S. Food and Drug Administration.
134 FDA label for approved methocarbamol from the official website of the U.S. Food and Drug Administration.
135 FDA label for approved prednisone from the official website of the U.S. Food and Drug Administration.
136 FDA label for approved allopurinol from the official website of the U.S. Food and Drug Administration.
137 FDA label for approved dexamethasone from the official website of the U.S. Food and Drug Administration.
138 FDA label for approved metaxalone from the official website of the U.S. Food and Drug Administration.
139 FDA label for approved sulindac from the official website of the U.S. Food and Drug Administration.
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143 FDA label for approved sulfasalazine from the official website of the U.S. Food and Drug Administration.
144 FDA label for approved ibuprofen from the official website of the U.S. Food and Drug Administration.
145 FDA label for approved terazosin from the official website of the U.S. Food and Drug Administration.
146 FDA label for approved erythromycin from the official website of the U.S. Food and Drug Administration.
147 FDA label for approved tolterodine from the official website of the U.S. Food and Drug Administration.
148 FDA label for approved sevelamer from the official website of the U.S. Food and Drug Administration.
149 FDA label for approved danazol from the official website of the U.S. Food and Drug Administration.
150 FDA label for approved aminocaproic acid from the official website of the U.S. Food and Drug Administration.
151 FDA label for approved trospium from the official website of the U.S. Food and Drug Administration.
152 FDA label for approved potassium citrate from the official website of the U.S. Food and Drug Administration.
153 FDA label for approved tranexamic acid from the official website of the U.S. Food and Drug Administration.
154 FDA label for approved trimethoprim from the official website of the U.S. Food and Drug Administration.
155 FDA label for approved estradiol from the official website of the U.S. Food and Drug Administration.
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