General Information of DFM (ID: F02396)
Name	Benzphetamine 50 mg tablet
Company	Mikart; PD-Rx Pharmaceuticals
Active Pharmaceutical Ingredient (API)	Benzphetamine		API Info click to show the detail info of this API
	Obesity		ICD-11: 5B81	Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E0F2PK	DIG Info	Calcium stearate	lubricant
	E01VHX	DIG Info	D&C red no. 30	Colorant
	E04KSN	DIG Info	Hexahydric alcohol	Diluent ...

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
Other protein families (OPF)
DBT Name: Heat shock factor 1 (HSF1)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	D&C red no. 30
Biological Activity	EC50 = 9054 nM (estimated based on the structural similarity with CHEMBL1339303 )					[1]
Structural Similarity	Tanimoto coefficient = 0.776859504
Tested Species	Mus musculus (Mouse)
UniProt ID	HSF1_MOUSE
DBT Name: Nuclear factor-kappa B (NFKB)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	D&C red no. 30
Biological Activity	EC50 = 122869 nM (estimated based on the structural similarity with CHEMBL1339303 )					[1]
Structural Similarity	Tanimoto coefficient = 0.776859504
Tested Species	Homo sapiens (Human)
UniProt ID	NFKB1_HUMAN ; NFKB2_HUMAN ; TF65_HUMAN

References
1	PubChem BioAssay data set.

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