General Information of DFM (ID: F18705)
Name	Ramipril 1.25 mg capsule
Company	Lupin Pharmaceuticals
Active Pharmaceutical Ingredient (API)	Ramipril		API Info click to show the detail info of this API
	Essential hypertension		ICD-11: BA00	Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E0M0IE	DIG Info	Ferric hydroxide oxide yellow	Colorant
	E0DS2Q	DIG Info	Meglumine	Buffering agent
	E05BSD	DIG Info	Titanium dioxide	Coating agent ...

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
Transferase (TFase)
DBT Name: Alglucerase (GBA)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Meglumine
Biological Activity	IC50 = 447000 nM (estimated based on the structural similarity with CHEMBL1933095 )					[1]
Structural Similarity	Tanimoto coefficient = 0.846153846
Tested Species	Bos taurus (Bovine)
UniProt ID	GLCM_BOVIN

References
1	Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes. Bioorg Med Chem. 2012 Jan 15; 20(2):641-9.

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