General Information of DFM (ID: F20029)
Name	Simethicone 80 mg tablet
Company	Cardinal Health
Active Pharmaceutical Ingredient (API)	Simethicone		API Info click to show the detail info of this API
	Irritable bowel syndrome		ICD-11: DD91	Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E0NN4I	DIG Info	Dextrin	Binding agent ...
	E04KSN	DIG Info	Hexahydric alcohol	Diluent ...
	E0Q3PU	DIG Info	Saccharose	Binding agent ...
	E0U2IQ	DIG Info	Stearyl stearate	Emollient ...

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
Cell line (CELL)
DBT Name: Colon cancer Caco-2 cells (Caco-2)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Dextrin
Biological Activity	Inhibition ratio > 55 % (tested by experiment)					[1]
Tested Species	Homo sapiens (Human)

References
1	Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.