Details of the Drug Formulation (DFM)
General Information of DFM (ID: F23500) | |||||
---|---|---|---|---|---|
Name |
Oxybutynin 5mg tablet
|
||||
Company |
Janssen Pharms
|
||||
Active Pharmaceutical Ingredient (API) | Oxybutynin | API Info click to show the detail info of this API | |||
Overactive bladder | ICD-11: GC50 | Approved | |||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E0SJ4H | DIG Info | Beta-D-lactose | Diluent ... | ||
E0F2PK | DIG Info | Calcium stearate | lubricant | ||
E0V2QO | DIG Info | Cellulose microcrystalline | Adsorbent ... | ||
E0LT6O | DIG Info | Food blue 1 aluminum lake | Colorant | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
---|---|---|---|---|---|---|
Cell line (CELL) | ||||||
DBT Name: Leukemia MT4 cells (MT4) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Food blue 1 aluminum lake | |||||
Biological Activity | IC50 = 1288.25 nM (estimated based on the structural similarity with CHEMBL202316 ) | [1] | ||||
Structural Similarity | Tanimoto coefficient = 0.78807947 | |||||
Tested Species | Homo sapiens (Human) | |||||
Cellosaurus ID | CVCL_2632 | |||||
References | |||||
---|---|---|---|---|---|
1 | Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues. J Med Chem. 2006 Feb 23; 49(4):1291-312. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.