General Information of DFM (ID: F23500)
Name
Oxybutynin 5mg tablet
Company
Janssen Pharms
Active Pharmaceutical Ingredient (API) Oxybutynin API Info click to show the detail info of this API
Overactive bladder ICD-11: GC50 Approved
Drug Inactive Ingredient (DIGs)
DIG ID DIG Info DIG Name DIG Functional Class
E0SJ4H DIG Info Beta-D-lactose Diluent ...
E0F2PK DIG Info Calcium stearate lubricant
E0V2QO DIG Info Cellulose microcrystalline Adsorbent ...
E0LT6O DIG Info Food blue 1 aluminum lake Colorant
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
      Cell line (CELL)
            DBT Name: Leukemia MT4 cells (MT4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Food blue 1 aluminum lake
                    Biological Activity IC50 = 1288.25 nM (estimated based on the structural similarity with CHEMBL202316 ) [1]
                    Structural Similarity Tanimoto coefficient = 0.78807947
                    Tested Species Homo sapiens (Human)
                    Cellosaurus ID CVCL_2632
References
1 Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues. J Med Chem. 2006 Feb 23; 49(4):1291-312.

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