Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23500) | |||||
|---|---|---|---|---|---|
| Name |
Oxybutynin 5mg tablet
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| Company |
Janssen Pharms
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| Active Pharmaceutical Ingredient (API) | Oxybutynin |
API Info
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| Overactive bladder | ICD-11: GC50 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0SJ4H | DIG Info | Beta-D-lactose | Diluent ... | ||
| E0F2PK | DIG Info | Calcium stearate | lubricant | ||
| E0V2QO | DIG Info | Cellulose microcrystalline | Adsorbent ... | ||
| E0LT6O | DIG Info | Food blue 1 aluminum lake | Colorant | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
|---|---|---|---|---|---|---|
| Cell line (CELL) | ||||||
| DBT Name: Leukemia MT4 cells (MT4) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Food blue 1 aluminum lake | |||||
| Biological Activity | IC50 = 1288.25 nM (estimated based on the structural similarity with CHEMBL202316 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.78807947 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| Cellosaurus ID | CVCL_2632 | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues. J Med Chem. 2006 Feb 23; 49(4):1291-312. | ||||
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