Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23751) | |||||
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| Name |
Fluocinonide 0.05% cream
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| Company |
A-S Medication Solutions
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| Active Pharmaceutical Ingredient (API) | Fluocinonide |
API Info
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| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E05EDA | DIG Info | 1,2,6-Hexanetriol | Emollient ... | ||
| E09QIG | DIG Info | Citric acid monohydrate | Acidulant ... | ||
| E0M1JK | DIG Info | Propylene glycol | Antimicrobial preservative ... | ||
| E0XV1Z | DIG Info | Stearyl alcohol | Emollient ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Oxidoreductase (ORase) | ||||||
| DBT Name: Albendazole monooxygenase (CYP3A4) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Propylene glycol | |||||
| Biological Activity | Inhibition ratio < 20 % (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CP3A4_HUMAN | |||||
| References | |||||
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| 1 | Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88. | ||||
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