Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E05RPP)
DIG Name
Oleyl alcohol
Synonyms    Click to Show/Hide the Synonyms of This DIG
OLEYL ALCOHOL; (Z)-octadec-9-en-1-ol; 143-28-2; cis-9-Octadecen-1-ol; Ocenol; Dermaffine; Lancol; Novol; Oceol; Oleol; Satol; Oleic alcohol; Oleo alcohol; (Z)-9-Octadecen-1-ol; Crodacol-O; Conditioner 1; Loxanol M; Atalco O; Siponol OC; Sipol O; (Z)-Octadec-9-enol; Cachalot O-1; Cachalot O-3; Cachalot O-8; H.D. eutanol; HD-Ocenol K; Loxanol 95; Unjecol 50; Unjecol 70; Unjecol 90; Oleoyl alcohol; Olive alcohol; Cachalot O-15; Crodacol A.10; Unjecol 110; HD oleyl alcohol CG; cis-9-Octadecenyl alcohol; Adol 34; Adol 80; Adol 85; Adol 90; HD-Ocenol 90/95; HD oleyl alcohol 70/75; HD oleyl alcohol 80/85; HD oleyl alcohol 90/95; (9Z)-octadec-9-en-1-ol; Witcohol 85; Witcohol 90; 9-Octadecen-1-ol, (Z)-; Adol 320; Adol 330; Adol 340; cis-octadecen-1-ol; 9-Octadecen-1-ol; (Z)-9-octadecenol; Oleylalcohol; HD-Eutanol; Octadec-9Z-enol; cis-9-octadecenol; UNII-172F2WN8DV; (9Z)-9-Octadecen-1-ol; 9Z-Octadecen-1-ol; Oleyl alcohol (NF); Oleyl alcohol [NF]; ( Z)-9-octadecenol; Witcohol 85 (TN); 9-Octadecen-1-ol, (9Z)-; Polyoxyl 10 oleyl ether; MFCD00002993; 9-Octadecen-1-ol, cis-; 172F2WN8DV; CHEBI:73504; 0leyl alcohol; 9-Octadecenol; Oleyl alcohol, ca. 60%, technical; Poly(oxy-1,2-ethanediyl), alpha-((Z)-9-octadecenyl)-omega-hydroxy-; cis-Oleyl alcohol; HSDB 6484; EINECS 205-597-3; NSC 10999; AI3-07620; Lipocol O; C18H36O; Anjecol 90N; Unjecol 90N; (Z)-oleyl alcohol; Anjecol 90NR; Unjecol 90NR; Francol OA-95; Fancol OA-95; cis 9 octadecen-1-ol; cis-9-0ctadecen-1-ol; 9(Z)-Octadecen-1-ol; HD-Echelon 90/95; cis-octadec-9-en-1-ol; DSSTox_CID_2010; Octadeca-9-cis-en-1-ol; EC 205-597-3; cis-.DELTA.9-Octadecenol; HD-Ocenol 90/95 V; SCHEMBL5668; (Z)-octadeca-9-en-1-ol; DSSTox_RID_76459; DSSTox_GSID_22010; (9Z)-9-Octadecen-1-ol #; Octadec-9-en-1-ol, (Z)-; CHEMBL2105350; DTXSID0022010; Oleyl alcohol, >=99% (GC); Oleyl alcohol, analytical standard; cis-Laquo deltaRaquo 9-Octadecenol; NSC10999; ZINC8214634; Tox21_200111; (9Z)-9-Octadecen-1-ol, 85%; 7025AA; LMFA05000213; NSC-10999; Oleyl alcohol, technical grade, 85%; AKOS004910411; Oleyl alcohol, technical, ~60% (GC); NCGC00164365-01; NCGC00164365-02; NCGC00257665-01; CAS-143-28-2; DB-007794; O0058; D05245; Q7086489; W-109512; UNII-13F4MW8Y9K component ALSTYHKOOCGGFT-KTKRTIGZSA-N; UNII-CH428W5O62 component ALSTYHKOOCGGFT-KTKRTIGZSA-N; UNII-UDR641JW8W component ALSTYHKOOCGGFT-KTKRTIGZSA-N; 3164D881-7E14-4979-9E60-58DDC0468323; Oleyl alcohol, United States Pharmacopeia (USP) Reference Standard
DIG Function
Emollient; Emulsifying agent; Penetration agent; Solubilizing agent
PubChem CID
5284499
Formula
C18H36O
Canonical SMILES
CCCCCCCC/C=C\\CCCCCCCCO
InChI
1S/C18H36O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h9-10,19H,2-8,11-18H2,1H3/b10-9-
InChIKey
ALSTYHKOOCGGFT-KTKRTIGZSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
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3D MOL 2D MOL
Physicochemical Properties Molecular Weight 268.5 Topological Polar Surface Area 20.2
XlogP 7.4 Complexity 175
Heavy Atom Count 19 Rotatable Bond Count 15
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Oxidoreductase (ORase)
            DBT Name: Squalene monooxygenase (SQLE) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 4000 nM (estimated based on the structural similarity with CHEMBL416643 ) [1]
                    Structural Similarity Tanimoto coefficient = 0.866666667
                    Tested Species Homo sapiens (Human)
                    UniProt ID ERG1_HUMAN
References
1 Inhibition of vertebrate squalene epoxidase by extended and truncated analogues of trisnorsqualene alcohol. J Med Chem. 1990 Jun; 33(6):1698-701.

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