Details of the Drug Inactive Ingredient (DIG)
| General Information of DIG (ID: E06ARW) | |||||
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| DIG Name |
Sucrose monolaurate
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| DIG Function |
Surfactant
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| Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
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| Potential-driven transporter (PDT) | ||||||
| DBT Name: Solute carrier SLCO2B1 (OATPB) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
 click to show the detail info of this DBT
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| Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Biological Activity | Inhibition ratio = 78.5 % (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | SO2B1_HUMAN | |||||
| Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Biological Activity | Ki = 47.7 uM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | SO2B1_HUMAN | |||||
| References | |||||
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| 1 | Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018. | ||||
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